Evidence map›Paper›PMID 23609394›Full record

ArticleJournal of clinical psychopharmacology2013

Association between therapeutic alliance, care satisfaction, and pharmacological adherence in bipolar disorder.

Louisa G Sylvia, Aleena Hay, Michael J Ostacher, David J Miklowitz, Andrew A Nierenberg, Michael E Thase, Gary S Sachs, Thilo Deckersbach, Roy H Perlis

Abstract readMulticenter Study
In one paragraph

Article in Journal of clinical psychopharmacology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Collaborative care approaches for people with severe mental illness.The Cochrane database of systematic reviews · 2024
    Pooled it
  2. Guideline
  3. Pooled it
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  16. Medication nonadherence in bipolar disorder: a narrative review.Therapeutic advances in psychopharmacology · 2018
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Louisa G SylviaBipolar Clinical and Research Program, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA. lsylvia2@partners.org
Aleena Hay
Michael J Ostacher
David J Miklowitz
Andrew A Nierenberg
Michael E Thase
Gary S Sachs
Thilo Deckersbach
Roy H Perlis

Funding

TREATMENT OF BIPOLAR DISORDER-278980001N01MH080001 · NIMH · MASSACHUSETTS GENERAL HOSPITAL · 1998 to 2003
$5.3M
1/2-Early Intervention for Youth at Risk for Bipolar DisorderR01MH093676 · NIMH · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI MIKLOWITZ, DAVID JAY · 2012 to 2016
$3.6M
NIMH NIH HHS N01 MH080001NIMH NIH HHS R01 MH093676
6 · The paper itself

Abstract

objectivesWe sought to understand the association of specific aspects of care satisfaction, such as patients' perceived relationship with their psychiatrist and access to their psychiatrist and staff, and therapeutic alliance with participants' likelihood to adhere to their medication regimens among patients with bipolar disorder.

methodsWe examined data from the multicenter Systematic Treatment Enhancement Program for Bipolar Disorder, an effectiveness study investigating the course and treatment of bipolar disorder. We expected that participants (n = 3037) with positive perceptions of their relationship with their psychiatrist and quality of psychopharmacologic care, as assessed by the Helping Alliance Questionnaire and Care Satisfaction Questionnaire, would be associated with better medication adherence. We utilized logistic regression models controlling for already established factors associated with poor adherence.

resultsPatients' perceptions of collaboration, empathy, and accessibility were significantly associated with adherence to treatment in individuals with bipolar disorder completing at least 1 assessment. Patients' perceptions of their psychiatrists' experience, as well as of their degree of discussing medication risks and benefits, were not associated with medication adherence.

conclusionsPatients' perceived therapeutic alliance and treatment environment impact their adherence to pharmacotherapy recommendations. This study may enable psychopharmacologists' practices to be structured to maximize features associated with greater medication adherence.

Indexed as

Patient SatisfactionPhysician-Patient RelationsAdultBipolar DisorderEmpathyFemaleFollow-Up StudiesHealth Services AccessibilityHumansLogistic ModelsLongitudinal StudiesMaleMedication AdherencePatient ParticipationProspective StudiesQuality of Health Care

Identifiers

PMID23609394
PMCPMC3873324

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.