ReviewJournal of applied genetics2013
Research progress in allele-specific expression and its regulatory mechanisms.
Review in Journal of applied genetics, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers, 1 of them a synthesis that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
45 citing papers in PubMed, 1 synthesis or guideline pooled it, 101 citations in OpenAlex.
- Exploring genetic variation that influences brain methylation in attention-deficit/hyperactivity disorder.Translational psychiatry · 2019Pooled it
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- Allelic structural variation at the NLR25-1 locus enhances defense against Pseudomonas syringae in kiwifruit.Genome biology · 2026Article
- Application of RNA markers in forensic body fluid analysis: from specificity and stability to polymorphism.International journal of legal medicine · 2026Review
- Systematic evaluation of single-cell RNA-seq analyses performance based on long-read sequencing platforms.Journal of advanced research · 2025Article
- Haplotype-resolved genome assembly provides new insights into the genomic origin of purple colour in Prunus mume.Plant biotechnology journal · 2025Article
- scRNA seq of an F1 cross of Marek's disease resistant and susceptible chickens identifies allele specific expression signatures enriched in transcription modulators.Scientific reports · 2025Article
- Polyploidization-driven transcriptomic dynamics in Medicago sativa neotetraploids: mRNA, smRNA and allele-specific gene expression.BMC plant biology · 2025Article
- DNA Methylation and Subgenome Dominance Reveal the Role of Lipid Metabolism in Jinhu Grouper Heterosis.International journal of molecular sciences · 2024Article
- Evolution and genetics of accessory gland transcriptome divergence between Drosophila melanogaster and D. simulans.Genetics · 2024Article
- High-quality genome assembly enables prediction of allele-specific gene expression in hybrid poplar.Plant physiology · 2024Article
- Article
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- Expression inheritance and constraints on cis- and trans-regulatory mutations underlying lotus color variation.Plant physiology · 2023Article
- Haplotype-resolved DNA methylome of African cassava genome.Plant biotechnology journal · 2023Article
- Transcriptome analysis of sugarcane reveals rapid defense response of SES208 to Xanthomonas albilineans in early infection.BMC plant biology · 2023Article
- Genome-wide analysis of NBS-LRR genes revealed contribution of disease resistance fromFrontiers in plant science · 2023Article
- Gene expression variations and allele-specific expression of two rice and their hybrid in caryopses at single-nucleus resolution.Frontiers in plant science · 2023Article
- Comparative transcriptomic analysis of maize ear heterosis during the inflorescence meristem differentiation stage.BMC plant biology · 2022Article
- Transposon insertions regulate genome-wide allele-specific expression and underpin flower colour variations in apple (Malus spp.).Plant biotechnology journal · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Although the majority of genes are expressed equally from both alleles, some genes are differentially expressed. Organisms possess characteristics to preferentially express a particular allele under regulatory factors, which is termed allele-specific expression (ASE). It is one of the important genetic factors that lead to phenotypic variation and can be used to identify the variance of gene regulation factors. ASE indicates mechanisms such as DNA methylation, histone modifications, and non-coding RNAs function. Here, we review a broad survey of progress in ASE studies, and what this simple yet very effective approach can offer in functional genomics, and possible implications toward our better understanding of the underlying mechanisms of complex traits.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.