ArticleBMC neuroscience2013
Differential expression of two novel odorant receptors in the locust (Locusta migratoria).
Article in BMC neuroscience, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed, 31 citations in OpenAlex.
- Anatomical Investigation Reveals a Second Olfactory System in Locusts.The Journal of comparative neurology · 2026Article
- Expanding the sensory horizon: chemosensory receptors beyond traditional olfactory and taste organs in insects.Science China. Life sciences · 2026Review
- Mutagenesis of Odorant Receptor CoreceptorInternational journal of molecular sciences · 2023Article
- A female-biased odorant receptor tuned to the lepidopteran sex pheromone in parasitoid Microplitis mediator guiding habitat of host insects.Journal of advanced research · 2023Article
- Serotonin/GABA receptors modulate odor input to olfactory receptor neuron in locusts.Frontiers in cellular neuroscience · 2023Article
- The specific expression patterns of sensory neuron membrane proteins are retained throughout the development of the desert locustCurrent research in insect science · 2023Article
- Odor-Induced Vomiting Is Combinatorially Triggered by Palp Olfactory Receptor Neurons That Project to the Lobus Glomerulatus in Locust Brain.Frontiers in physiology · 2022Article
- Molecular characterization and expression of sensory neuron membrane proteins in the parasitoid Microplitis mediator (Hymenoptera: Braconidae).Insect science · 2020Article
- Expression of odorant-binding proteins in mouthpart palps of the desert locust Schistocerca gregaria.Insect molecular biology · 2019Article
- Expressions of Olfactory Proteins in Locust Olfactory Organs and a Palp Odorant Receptor Involved in Plant Aldehydes Detection.Frontiers in physiology · 2018Article
- Localization of Odorant Receptor Genes in Locust Antennae by RNA In Situ Hybridization.Journal of visualized experiments : JoVE · 2017Article
- In Search for Pheromone Receptors: Certain Members of the Odorant Receptor Family in the Desert LocustInternational journal of biological sciences · 2017Article
- Two Olfactory Pathways to Detect Aldehydes on Locust Mouthpart.International journal of biological sciences · 2017Article
- A broadly tuned odorant receptor in neurons of trichoid sensilla in locust, Locusta migratoria.Insect biochemistry and molecular biology · 2016Article
- MicroRNA-276 promotes egg-hatching synchrony by up-regulating brm in locusts.Proceedings of the National Academy of Sciences of the United States of America · 2016Article
- Article
- Identification and functional analysis of olfactory receptor family reveal unusual characteristics of the olfactory system in the migratory locust.Cellular and molecular life sciences : CMLS · 2015Article
- Variant ionotropic receptors are expressed in olfactory sensory neurons of coeloconic sensilla on the antenna of the desert locust (Schistocerca gregaria).International journal of biological sciences · 2013Article
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundOlfaction in animals is important for host localization, mating and reproduction in heterogeneous chemical environments. Studying the molecular basis of olfactory receptor neurons (ORNs) systems can elucidate the evolution of olfaction and associated behaviours. Odorant receptors (ORs) in insects have been identified, particularly in the holometabolous model Drosophila, and some of them have been functionally studied. However, ORs in the locust-a hemimetabolous model insect and the most important insect crop pest-have not yet been identified, hindering our understanding of locust olfaction. Here, we report for the first time four putative ORs in Locusta migratoria: LmigOR1, LmigOR2, LmigOR3 and LmigOR4.
resultsThese four putative OR genes encoded proteins with amino acids of 478, 436, 413 and 403 respectively. Sequence identity among them ranged from 19.7% to 35.4%. All ORs were tissue-specifically expressed in olfactory organs, without sex-biased characteristics. However, LmigOR1, LmigOR3 and LmigOR4 were only expressed in the antenna, while LmigOR2 could also be detected in mouthparts. In situ hybridization demonstrated that the LmigOR1antisense probe labelled olfactory receptor neurons (ORNs) in almost all segments of the antenna, but only a few segments housed ORNs expressing LmigOR2. The number of neurons labelled by LmigOR1 antisense probes in each antennal segment was much greater (>10 neurons/segment) than that labelled by LmigOR2 probes (generally 1-3 neurons/segment). Furthermore, some of the labelled neurons could be attributed to the basiconic sensilla, but LmigOR1 and LmigOR2 were expressed in different subtypes.
conclusionsOur results strongly suggested that these newly discovered genes encode locust ORs and the differential expression patterns of LmigOR1 and LmigOR2 implied distinct functions. These results may offer insights into locust olfaction and contribute to the understanding of the evolution of insect chemoreception.
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