ArticleJournal of obesity2013
Comparison among T1-weighted magnetic resonance imaging, modified dixon method, and magnetic resonance spectroscopy in measuring bone marrow fat.
Article in Journal of obesity, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
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Who cites it
26 citing papers in PubMed, 63 citations in OpenAlex.
- Effect of caloric restriction on organ size and its contribution to metabolic adaptation: an ancillary analysis of CALERIE 2.Scientific reports · 2025Trial
- Effect of 2-year caloric restriction on organ and tissue size in nonobese 21- to 50-year-old adults in a randomized clinical trial: the CALERIE study.The American journal of clinical nutrition · 2021Trial
- Deep Learning for Analysis of Bone Marrow Adiposity: Breakthroughs from Recent Large-Scale Analyses in the UK Biobank.Current osteoporosis reports · 2026Review
- Quantitative MRI Dixon signal drop and fat fraction for differentiating bone marrow lesions: a two-center prospective analysis.European radiology experimental · 2025Article
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- Quantitative MR Analysis of Changes in the Radius Bone Marrow in Osteoporosis.Journal of osteoporosis · 2023Article
- Magnetic Resonance Imaging to Assess Body Composition Change in Adolescents With Obesity After Sleeve Gastrectomy.Journal of pediatric gastroenterology and nutrition · 2022Article
- The Effect of Roux-en-Y Gastric Bypass on Bone Marrow Adipose Tissue and Bone Mineral Density in Postmenopausal, Nondiabetic Women.Obesity (Silver Spring, Md.) · 2021Article
- Evaluation of bone marrow infiltration in multiple myeloma using whole-body diffusion-weighted imaging and T1-weighted water-fat separation Dixon.Quantitative imaging in medicine and surgery · 2021Article
- Fat fraction quantification of lumbar spine: comparison of T1-weighted two-point Dixon and single-voxel magnetic resonance spectroscopy in diagnosis of multiple myeloma.Diagnostic and interventional radiology (Ankara, Turkey) · 2020Article
- Fat and bone: the multiperspective analysis of a close relationship.Quantitative imaging in medicine and surgery · 2020Review
- Regional variation in paraspinal muscle composition using chemical shift encoding-based water-fat MRI.Quantitative imaging in medicine and surgery · 2020Article
- Bone Marrow Adiposity: Basic and Clinical Implications.Endocrine reviews · 2019Review
- Imaging of non-neuronopathic Gaucher disease: recent advances in quantitative imaging and comprehensive assessment of disease involvement.Insights into imaging · 2019Review
- Simultaneous Estimation of the Fat Fraction and R₂Korean journal of radiology · 2019Article
- Fat Quantification in the Vertebral Body: Comparison of Modified Dixon Technique with Single-Voxel Magnetic Resonance Spectroscopy.Korean journal of radiology · 2019Article
- Marrow adipose tissue imaging in humans.Bone · 2019Review
- Osteoporosis: what the clinician needs to know?Quantitative imaging in medicine and surgery · 2018Review
- Short- and midterm reproducibility of marrow fat measurements using mDixon imaging in healthy postmenopausal women.Skeletal radiology · 2016Article
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
introductionAn increasing number of studies are utilizing different magnetic resonance (MR) methods to quantify bone marrow fat due to its potential role in osteoporosis. Our aim is to compare the measurements of bone marrow fat among T1-weighted magnetic resonance imaging (MRI), modified Dixon method (also called fat fraction MRI (FFMRI)), and magnetic resonance spectroscopy (MRS).
methodsContiguous MRI scans were acquired in 27 Caucasian postmenopausal women with a modified Dixon method (i.e., FFMRI). Bone marrow adipose tissue (BMAT) of T1-weighted MRI and bone marrow fat fraction of the L3 vertebra and femoral necks were quantified using SliceOmatic and Matlab. MRS was also acquired at the L3 vertebra.
resultsCorrelation among the three MR methods measured bone marrow fat fraction and BMAT ranges from 0.78 to 0.88 (P < 0.001) in the L3 vertebra. Correlation between BMAT measured by T1-weighted MRI and bone marrow fat fraction measured by modified FFMRI is 0.86 (P < 0.001) in femoral necks.
conclusionThere are good correlations among T1-weighted MRI, FFMRI, and MRS for bone marrow fat quantification. The inhomogeneous distribution of bone marrow fat, the threshold segmentation of the T1-weighted MRI, and the ambiguity of the FFMRI may partially explain the difference among the three methods.
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