Evidence map›Paper›PMID 23606894›Full record

ArticleNano today2013

Theranostic agents for intracellular gene delivery with spatiotemporal imaging.

Jennifer M Knipe, Jonathan T Peters, Nicholas A Peppas

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Nano today, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Current and emerging approaches to manage chronic inflammatory gut disorders.Frontiers in cellular and infection microbiology · 2026
    Review
  2. Review
  3. Growth Dynamics of Colloidal Silver-Gold Core-Shell Nanoparticles Studied byThe journal of physical chemistry. C, Nanomaterials and interfaces · 2021
    Article
  4. Article
  5. Intelligent recognitive systems in nanomedicine.Current opinion in chemical engineering · 2014
    Article
  6. Review
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Jennifer M KnipeDepartment of Chemical Engineering, C0400, The University of Texas at Austin, Austin, TX 78712 (USA).
Jonathan T Peters
Nicholas A Peppas

Funding

TRANS-NETWORK PROJECTSU54CA143837 · NCI · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI CRISTINI, VITTORIO · 2009 to 2014
$10.8M
pH Sensitive Complex Hydrogels for Protein Drug ReleaseR01EB000246 · NIBIB · UNIVERSITY OF TEXAS AUSTIN · PI LOWMAN, ANTHONY M, PEPPAS, NICHOLAS A · 2002 to 2014
$3.8M
Thermally Responsive Magnetic-Hydrogel Nanocomposites for Advanced Drug DeliveryR21EB012726 · NIBIB · UNIVERSITY OF TEXAS AT AUSTIN · PI PEPPAS, NICHOLAS A · 2011 to 2012
$393k
NCI NIH HHS U54 CA143837NIBIB NIH HHS R01 EB000246NIBIB NIH HHS R21 EB012726
6 · The paper itself

Abstract

Gene therapy is the modification of gene expression to treat a disease. However, efficient intracellular delivery and monitoring of gene therapeutic agents is an ongoing challenge. Use of theranostic agents with suitable targeted, controlled delivery and imaging modalities has the potential to greatly advance gene therapy. Inorganic nanoparticles including magnetic nanoparticles, gold nanoparticles, and quantum dots have been shown to be effective theranostic agents for the delivery and spatiotemporal tracking of oligonucleotides

Indexed as

gene deliverygold nanoparticlesimagingmagnetic nanoparticlesquantum dots

Identifiers

PMID23606894
PMCPMC3627379

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.