Evidence map›Paper›PMID 23606822›Full record

ArticleCurrent pediatric reviews2009

RESEARCH ADVANCES IN NEUROBLASTOMA IMMUNOTHERAPY.

Latania Y Booker, Titilope A Ishola, Kanika A Bowen, Dai H Chung

Abstract read
In one paragraph

Article in Current pediatric reviews, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Latania Y BookerDepartment of Surgery The University of Texas Medical Branch Galveston, TX 77555.
Titilope A Ishola
Kanika A Bowen
Dai H Chung

Funding

Surgical Studies on the Role on Gastrin-releasing Peptide in NeuroblastomaR01DK061470 · NIDDK · VANDERBILT UNIVERSITY MEDICAL CENTER · PI CHUNG, DAI H. · 2003 to 2018
$4.7M
Mechanisms of Gastrin-Releasing Peptide-Mediated Neuroblastoma GrowthF31DK079422 · NIDDK · UNIVERSITY OF TEXAS MED BR GALVESTON · PI FASIPE, TITILOPE A · 2007 to 2008
$41k
NIDDK NIH HHS F31 DK079422NIDDK NIH HHS R01 DK061470
6 · The paper itself

Abstract

Neuroblastoma is the third most common pediatric cancer in the United States and is responsible for 15% of pediatric cancer-related deaths. Despite major advances in multimodal therapy, the clinical outcome for several patients remains poor. Due to the desperate need for innovativation and improved success in the treatment and management of neuroblastoma, research interests in immunotherapy have been on the rise in recent years. Current immunotherapeutic approaches under investigation include antibodies targeting the neuroblastoma antigen GD2, cytokine stimulation of immune cells, use of immunocytokine conjugates, radioimmunotherapy, and tumor-primed dendritic cells. Immunotherapy could serve as a safe alternative or adjunct to current therapeutic protocols and would presumptively have fewer deleterious effects making it more favorable to patients.

Indexed as

antibody-mediated therapycell-mediated therapycytokine-mediated therapyimmunotherapyNeuroblastoma

Identifiers

PMID23606822
PMCPMC3629732

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.