ReviewMediators of inflammation2013
Helicobacter pylori infection, chronic inflammation, and genomic transformations in gastric MALT lymphoma.
Review in Mediators of inflammation, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.
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Who cites it
17 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Pooled it
- Article
- The Human Microbiota and Skin Cancer.International journal of molecular sciences · 2022Review
- Role in staging and prognostic value of pretherapeutic F-18 FDG PET/CT in patients with gastric MALT lymphoma without high-grade transformation.Scientific reports · 2021Article
- A retrospective study assessing the acceleration effect of type I Helicobacter pylori infection on the progress of atrophic gastritis.Scientific reports · 2021Article
- From Microbiome to Inflammation: The Key Drivers of Cervical Cancer.Frontiers in microbiology · 2021Review
- Mutational analysis of extranodal marginal zone lymphoma using next generation sequencing.Oncology letters · 2020Article
- Relevance on the diagnosis of malignant lymphoma of the salivary gland.World journal of clinical cases · 2020Review
- Prognostic Value of Accumulative Expression of COX-2 and p53 in Small and Diffuse Large B Cell Lymphoma.Pathology oncology research : POR · 2020Article
- Breast Implant-Associated Anaplastic Large Cell Lymphoma (ALCL): A Case Report.The American journal of case reports · 2017Article
- Validation of a Novel Immunoline Assay for Patient Stratification according to Virulence of the InfectingJournal of immunology research · 2017Article
- Establishment of a combination scoring method for diagnosis of ocular adnexal lymphoproliferative disease.PloS one · 2017Article
- Microbiota as a mediator of cancer progression and therapy.Translational research : the journal of laboratory and clinical medicine · 2017Review
- Concurrent gastric and pulmonary mucosa-associated lymphoid tissue lymphomas with pre-existing intrinsic chronic inflammation: a case report and a review of the literature.Gut and liver · 2015Review
- A clinical perspective on the role of chronic inflammation in gastrointestinal cancer.Clinical and experimental gastroenterology · 2014Review
- Role of Helicobacter pylori virulence factor cytotoxin-associated gene A in gastric mucosa-associated lymphoid tissue lymphoma.World journal of gastroenterology · 2013Review
- Concurrent Adenocarcinoma and Mucosa-Associated Lymphoid Tissue Lymphoma of the Stomach: A Case Report and Narrative Literature Review.Case reports in oncologyArticle
Corrections and comments
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Nowadays, it is believed that the main role in the development of gastric mucosa-associated lymphoid tissue (MALT) lymphoma plays Helicobacter pylori infection. This world-wide distributed bacteria is in charge of most cases of not only upper gastrointestinal tract disorders but also some of extragastric problems. Constant stimulation of the immune system causes a B-lymphocytes proliferation, which is considered to be responsible for the neoplastic transformation. On the other hand, there are 10%-20% of patients who do not respond to Helicobacter pylori eradication treatment. This group has often a chromosome translocation, which suggests that there is another unknown, so far, pathogenetic mechanism of MALT lymphoma. Majority of genetic abnormalities are connected with nuclear factor-κB (NF-κB) pathway, which activates the uncontrolled proliferation of neoplastic cells. Translocations already described in studies are t(11;18)(q21;q21), which is the most common, t(14;18)(q32;q21), t(14;18)(q32;q21), and t(3;14)(p14.1;q32). This non-Hodgkin's lymphoma is an indolent type originated outside lymph nodes. In more than 50% of cases, it occurs in the stomach. Occasionally, it can be found in salivary and thyroid gland, lung, breast, bladder, skin, or any other place in the human body. This paper is a review of the current knowledge on etiology, pathogenesis, treatment, and follow-up of gastric MALT lymphoma.
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