Evidence map›Paper›PMID 23606473›Full record

ReviewNMR in biomedicine2013

In vivo MRI cell tracking using perfluorocarbon probes and fluorine-19 detection.

Eric T Ahrens, Jia Zhong

Abstract readReview
In one paragraph

Review in NMR in biomedicine, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 74 papers.

0numbers the graph read from it
0cells of the map it votes in
74citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

74 citing papers in PubMed.

  1. Trial
  2. Article
  3. Review
  4. Review
  5. Polymeric (Poly(lactic-ACS omega · 2025
    Article
  6. Article
  7. Review
  8. Review
  9. Article
  10. Article
  11. Perfluorocarbons: A perspective of theranostic applications and challenges.Frontiers in bioengineering and biotechnology · 2023
    Review
  12. Article
  13. Direct Cell Radiolabeling forChemical reviews · 2022
    Review
  14. Review
  15. Review
  16. Frontiers in bioengineering and biotechnology · 2022
    Article
  17. Review
  18. Article
  19. Article
  20. Nanoparticles for "two color"Journal of colloid and interface science · 2020
    Article

14 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Eric T AhrensDepartment of Biological Sciences and Pittsburgh NMR Center for Biomedical Research, Carnegie Mellon University, Pittsburgh, PA 15213, USA. eta@cmu.edu
Jia Zhong

Funding

A MULTIDISCIPLINARY NMR CENTER FOR BIOMEDICAL RESEARCHP41EB001977 · NIBIB · MELLON PITTS CORPORATION (MPC CORP) · PI HO, CHIEN · 2003 to 2013
$12.5M
CLINICAL TRANSLATION OF 19F MRI TO VISUALIZE CANCER IMMUNOTHERAPEUTIC CELLSR01CA134633 · NCI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI AHRENS, ERIC T., COHEN, EZRA · 2009 to 2021
$4.4M
NCI NIH HHS R01 CA134633NCI NIH HHS R01-CA134633NIBIB NIH HHS P41 EB001977NIBIB NIH HHS P41-EB001977
6 · The paper itself

Abstract

This article presents a brief review of preclinical in vivo cell-tracking methods and applications using perfluorocarbon (PFC) probes and fluorine-19 ((19) F) MRI detection. Detection of the (19) F signal offers high cell specificity and quantification ability in spin density-weighted MR images. We discuss the compositions of matter, methods and applications of PFC-based cell tracking using ex vivo and in situ PFC labeling in preclinical studies of inflammation and cellular therapeutics. We also address the potential applicability of (19) F cell tracking to clinical trials.

Indexed as

FluorineFluorocarbonsMagnetic Resonance ImagingMolecular ProbesAnimalsCell TrackingContrast MediaHumansContrast MediaFluorineFluorocarbonsMolecular Probes

Identifiers

PMID23606473
PMCPMC3893103

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.