ArticleJournal of experimental botany2013
In vivo speciation studies and antioxidant properties of bromine in Laminaria digitata reinforce the significance of iodine accumulation for kelps.
Article in Journal of experimental botany, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed, 56 citations in OpenAlex.
- The Effect of Bromine and Iodine on the Plant Growth, Phytochemical Composition and Antioxidant Capacity of Dandelion (Molecules (Basel, Switzerland) · 2025Article
- A Transcriptomic Study on the Toxic Effects of Iodide (ICurrent issues in molecular biology · 2025Article
- Alleviative Effect of Iodine Pretreatment on the Stress ofInternational journal of molecular sciences · 2023Article
- Soybean Plants Exposed to Low Concentrations of Potassium Iodide Have Better Tolerance to Water Deficit through the Antioxidant Enzymatic System and Photosynthesis Modulation.Plants (Basel, Switzerland) · 2023Article
- Naturally Occurring Organohalogen Compounds-A Comprehensive Review.Progress in the chemistry of organic natural products · 2023Review
- Article
- Emission of volatile halogenated compounds, speciation and localization of bromine and iodine in the brown algal genome model Ectocarpus siliculosus.Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry · 2018Article
- Environmental Control of Vanadium Haloperoxidases and Halocarbon Emissions in Macroalgae.Marine biotechnology (New York, N.Y.) · 2018Review
- Infection of the brown alga Ectocarpus siliculosus by the oomycete Eurychasma dicksonii induces oxidative stress and halogen metabolism.Plant, cell & environment · 2016Article
- Response of wheat and pea seedlings on increase of bromine concentration in the growth medium.Environmental science and pollution research international · 2015Article
- A newly designed curcumin analog Y20 mitigates cardiac injury via anti-inflammatory and anti-oxidant actions in obese rats.PloS one · 2015Article
- Superoxide production by a manganese-oxidizing bacterium facilitates iodide oxidation.Applied and environmental microbiology · 2014Article
- Iodine contributes to osmotic acclimatisation in the kelp Laminaria digitata (Phaeophyceae).Planta · 2014Article
Corrections and comments
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Authors and funding
17 authors at 10 institutions in 6 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The metabolism of bromine in marine brown algae remains poorly understood. This contrasts with the recent finding that the accumulation of iodide in the brown alga Laminaria serves the provision of an inorganic antioxidant - the first case documented from a living system. The aim of this study was to use an interdisciplinary array of techniques to study the chemical speciation, transformation, and function of bromine in Laminaria and to investigate the link between bromine and iodine metabolism, in particular in the antioxidant context. First, bromine and iodine levels in different Laminaria tissues were compared by inductively coupled plasma MS. Using in vivo X-ray absorption spectroscopy, it was found that, similarly to iodine, bromine is predominantly present in this alga in the form of bromide, albeit at lower concentrations, and that it shows similar behaviour upon oxidative stress. However, from a thermodynamic and kinetic standpoint, supported by in vitro and reconstituted in vivo assays, bromide is less suitable than iodide as an antioxidant against most reactive oxygen species except superoxide, possibly explaining why kelps prefer to accumulate iodide. This constitutes the first-ever study exploring the potential antioxidant function of bromide in a living system and other potential physiological roles. Given the tissue-specific differences observed in the content and speciation of bromine, it is concluded that the bromide uptake mechanism is different from the vanadium iodoperoxidase-mediated uptake of iodide in L. digitata and that its function is likely to be complementary to the iodide antioxidant system for detoxifying superoxide.
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