Evidence map›Paper›PMID 23606236›Full record

ReviewJournal of cellular biochemistry2013

SWI/SNF in cardiac progenitor cell differentiation.

Ienglam Lei, Liu Liu, Mai Har Sham, Zhong Wang

Abstract readReview
In one paragraph

Review in Journal of cellular biochemistry, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Review
  9. Improving cardiac reprogramming for heart regeneration.Current opinion in organ transplantation · 2016
    Review
  10. Article
  11. Derivation of cardiac progenitor cells from embryonic stem cells.Journal of visualized experiments : JoVE · 2015
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Ienglam LeiDepartment of Cardiac Surgery, Cardiovascular Research Center, University of Michigan Medical School, North Campus Research Complex, Ann Arbor, Michigan, 48109; Li Ka Shing Faculty of Medicine, Departments of Biochemistry, The University of Hong Kong, Pokfulam, Hong Kong, China.
Liu Liu
Mai Har Sham
Zhong Wang

Funding

Epigenetic control of multipotent cardiac progenitor cell differentiationR01HL109054 · NHLBI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI WANG, ZHONG · 2012 to 2016
$1.9M
NHLBI NIH HHS R01 HL109054NHLBI NIH HHS R01 HL109054‐01
6 · The paper itself

Abstract

Cardiogenesis requires proper specification, proliferation, and differentiation of cardiac progenitor cells (CPCs). The differentiation of CPCs to specific cardiac cell types is likely guided by a comprehensive network comprised of cardiac transcription factors and epigenetic complexes. In this review, we describe how the ATP-dependent chromatin remodeling SWI/SNF complexes work synergistically with transcription and epigenetic factors to direct specific cardiac gene expression during CPC differentiation. Furthermore, we discuss how SWI/SNF may prime chromatin for cardiac gene expression at a genome-wide level. A detailed understanding of SWI/SNF-mediated CPC differentiation will provide important insight into the etiology of cardica defects and help design novel therapies for heart disease.

Indexed as

AnimalsCell DifferentiationChromatin Assembly and DisassemblyChromosomal Proteins, Non-HistoneHumansStem CellsTranscription FactorsChromosomal Proteins, Non-HistoneSWI-SNF-B chromatin-remodeling complexTranscription FactorsATP-DEPENDENT CHROMATIN REMODELNGCARDIAC PROGENITOR CELLDIFFERENTIATIONSWI/SNF

Identifiers

PMID23606236
PMCPMC4174539

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.