Evidence map›Paper›PMID 23605785›Full record

ReviewDrugs & aging2013

Therapeutic management of primary immunodeficiency in older patients.

Nisha Verma, Anthony Thaventhiran, Benjamin Gathmann, ESID Registry Working Party, James Thaventhiran, Bodo Grimbacher

Abstract readReview
PubMed Publisher
In one paragraph

Review in Drugs & aging, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 19 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Nisha VermaDepartment of Immunology and Molecular Pathology, Royal Free Hospital and University College London, London, UK.
Anthony Thaventhiran
Benjamin Gathmann
ESID Registry Working Party
James Thaventhiran
Bodo Grimbacher
University of Freiburg · DEThe Royal Free Hospital · GBUniversity College London · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Primary immunodeficiency disease (PID) has traditionally been viewed as a group of illnesses seen in the paediatric age group. New advances in diagnosis and treatment have led to an increase in the number of elderly PID patients. However, there is lack of research evidence on which to base clinical management in this group of patients. Management decisions often have to be based therefore on extrapolations from other patient cohorts or from younger patients. Data from the European Society for Immunodeficiencies demonstrates that the vast majority of elderly patients suffer from predominantly antibody deficiency syndromes. We review the management of PID disease in the elderly, with a focus on antibody deficiency disease.

Indexed as

AgammaglobulinemiaAgedAge FactorsAnti-Bacterial AgentsBone Marrow TransplantationCommon Variable ImmunodeficiencyGenetic Diseases, X-LinkedGenetic TherapyHumansImmunoglobulins, IntravenousAnti-Bacterial AgentsImmunoglobulins, Intravenous

Identifiers

PMID23605785
OpenAlexW2066757618

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.