Evidence map›Paper›PMID 23605168›Full record

ReviewCurrent allergy and asthma reports2013

Update on the treatment of juvenile idiopathic arthritis.

Julia G Harris, Elizabeth A Kessler, James W Verbsky

Open access · greenAbstract readReview
In one paragraph

Review in Current allergy and asthma reports, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 48 citations in OpenAlex.

  1. Article
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  12. Article
  13. Macrophage activation syndrome and cytokine-directed therapies.Best practice & research. Clinical rheumatology · 2014
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Julia G HarrisDivision of Rheumatology, Department of Pediatrics, Medical College of Wisconsin, 9000 W. Wisconsin Ave, Wauwatosa, WI 53226, USA. jgharris@mcw.edu
Elizabeth A Kessler
James W Verbsky
Medical College of Wisconsin · US

Funding

Clincal and Translational Science AwardUL1TR000055 · NCATS · MEDICAL COLLEGE OF WISCONSIN · PI SHAKER, REZA NONE · 2012 to 2015
$11.3M
Cytokines in T Regulatory Cell FunctionK08AI072023 · NIAID · MEDICAL COLLEGE OF WISCONSIN · PI VERBSKY, JAMES W · 2010 to 2013
$537k
NCATS NIH HHS UL1 TR000055NIAID NIH HHS K08 AI072023
6 · The paper itself

Abstract

Juvenile idiopathic arthritis (JIA) is one of the most common chronic diseases of childhood. Although the pathophysiology behind this disease is poorly understood, there are effective treatments for JIA based on the subtype of disease. Treatment options include non-steroidal anti-inflammatory drugs, intra-articular glucocorticoid injections, and traditional disease modifying anti-rheumatic drugs such as methotrexate. In the past decade, the use of biologic therapy in JIA, including tumor necrosis factor inhibitors, interleukin-1 inhibitors, and interleukin-6 inhibitors, has dramatically increased with promising outcomes.

Indexed as

Anti-Inflammatory Agents, Non-SteroidalAntirheumatic AgentsArthritis, JuvenileBiological TherapyGlucocorticoidsHumansImmunologic FactorsInterleukin-1Interleukin-6MethotrexateTumor Necrosis Factor-alphaAnti-Inflammatory Agents, Non-SteroidalAntirheumatic AgentsGlucocorticoidsImmunologic FactorsInterleukin-1Interleukin-6MethotrexateTumor Necrosis Factor-alpha

Identifiers

PMID23605168
PMCPMC3729726
OpenAlexW2070538141

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.