ArticleMycotoxin research2009
Gliotoxin in Aspergillus fumigatus: an example that mycotoxins are potential virulence factors.
Article in Mycotoxin research, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 36 citations in OpenAlex.
- Editing gliA, gliP and gliZ of Aspergillus fumigatus Using CRISPR/Cas System Renders Fungus Incapable to Produce Gliotoxin.Molecular biotechnology · 2026Article
- Genome mining of albocandins A-E fromRSC advances · 2025Article
- Article
- Mycotoxins - Determination of aflatoxins, ochratoxin A, free ochratoxin α, gliotoxin, citrinin, and dihydrocitrinone in urine by LC-MS/MS: Biomonitoring Method - Translation of the German version from 2025.The MAK collection for occupational health and safety · 2025Article
- First genome-scale insights into the virulence of the snow mold causal fungus Microdochium nivale.IMA fungus · 2023Article
- Epipolythiodioxopiperazine-Based Natural Products: Building Blocks, Biosynthesis and Biological Activities.Chembiochem : a European journal of chemical biology · 2022Review
- Therapeutic Potential of Green Synthesized Gold Nanoparticles Using Extract ofJournal of fungi (Basel, Switzerland) · 2022Article
- The International Space Station Environment Triggers Molecular Responses inFrontiers in microbiology · 2022Article
- Effective Inhibition of Invasive Pulmonary Aspergillosis by Silver Nanoparticles Biosynthesized withNanomaterials (Basel, Switzerland) · 2021Article
- Malignant Keratitis Caused by a Highly-Resistant Strain of Fusarium Tonkinense from theJournal of fungi (Basel, Switzerland) · 2021Article
- The Peroxiredoxin Asp f3 Acts as Redox Sensor inGenes · 2021Article
- Functional Role ofToxins · 2021Article
- Aspergillosis, Avian Species and the One Health Perspective: The Possible Importance of Birds in Azole Resistance.Microorganisms · 2020Review
- In vitro study on aspects of molecular mechanisms underlying invasive aspergillosis caused by gliotoxin and fumagillin, alone and in combination.Scientific reports · 2020Article
- The Pheromone Module SteC-MkkB-MpkB-SteD-HamE Regulates Development, Stress Responses and Secondary Metabolism inFrontiers in microbiology · 2020Article
- Structural Diversity and Biological Activities of the Cyclodipeptides from Fungi.Molecules (Basel, Switzerland) · 2017Review
- Molecular Insights into Pathogenesis and Infection withThe Malaysian journal of medical sciences : MJMS · 2017Review
- Immunochemical analysis of fumigaclavine mycotoxins in respiratory tissues and in blood serum of birds with confirmed aspergillosis.Mycotoxin research · 2015Article
- Rational and combinatorial tailoring of bioactive cyclic dipeptides.Frontiers in microbiology · 2015Review
- Production and characterization of antibodies against fumigaclavine A.Mycotoxin research · 2009Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Moulds produce several different mycotoxins that may improve their chance of survival in particular environments. For example, Aspergillus fumigatus, an important human pathogen, produces several mycotoxins including gliotoxin. This secondary metabolite, a small lipid soluble dipeptide, exerts toxic effects on phagocytic cells and T-lymphocytes at low concentrations in vitro. A. fumigatus also produces high levels of gliotoxin in vivo, and this suggests that host defense mechanisms might be impaired by this metabolite during host infection. In the past few years, the genes responsible for the production of gliotoxin in A. fumigatus have been identified and more recently gliotoxin-minus mutants have been used in animal experiments to ascertain the biological role of this product. Mycotoxins have also been shown to act as virulence factors in some fungal infections of insects and plants.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.