ArticleJournal of genetic counseling2013
"Nothing is absolute in life": understanding uncertainty in the context of psychiatric genetic counseling from the perspective of those with serious mental illness.
Article in Journal of genetic counseling, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 1 synthesis or guideline pooled it.
- The Efficacy of Genetic Counseling for Psychiatric Disorders: a Meta-Analysis.Journal of genetic counseling · 2017Pooled it
- A pilot randomized clinical trial evaluating the impact of genetic counseling for serious mental illnesses.The Journal of clinical psychiatry · 2016Trial
- Evaluation of Team-Based Genetic Counseling Services in Korea.Journal of Korean medical science · 2026Article
- Genetic counselling for psychiatric conditions: exploring current perceptions of family physicians and psychiatrists in Portugal.Journal of community genetics · 2025Article
- Global trends and themes in genetic counseling research.European journal of human genetics : EJHG · 2023Article
- Influences of race and clinical variables on psychiatric genetic research participation: Results from a schizophrenia sample.PloS one · 2023Article
- Psychiatric genetic counseling for patients with schizophrenia and their families.Frontiers in psychiatry · 2022Article
- Teenagers and Precision Psychiatry: A Window of Opportunity.Public health genomics · 2021Article
- Evidence-Based Genetic Counseling for Psychiatric Disorders: A Road Map.Cold Spring Harbor perspectives in medicine · 2020Review
- Training to Provide Psychiatric Genetic Counseling: How Does It Impact Recent Graduates' and Current Students' Readiness to Provide Genetic Counseling for Individuals with Psychiatric Illness and Attitudes towards this Population?Journal of genetic counseling · 2018Article
- Prenatal genetic counselling for psychiatric disorders.Prenatal diagnosis · 2017Article
- Attitudes about Future Genetic Testing for Posttraumatic Stress Disorder and Addiction among Community-Based Veterans.Frontiers in psychiatry · 2017Article
- Genetic Counselling for Psychiatric Disorders: Accounts of Psychiatric Health Professionals in the United Kingdom.Journal of genetic counseling · 2016Article
- Known unknowns: building an ethics of uncertainty into genomic medicine.BMC medical genomics · 2016Article
- Defining Our Clinical Practice: The Identification of Genetic Counseling Outcomes Utilizing the Reciprocal Engagement Model.Journal of genetic counseling · 2016Article
- Communication of Psychiatric Risk in 22q11.2 Deletion Syndrome: A Pilot Project.Journal of genetic counseling · 2016Article
- Genetic and family counselling for schizophrenia: Where do we stand now?The South African journal of psychiatry : SAJP : the journal of the Society of Psychiatrists of South Africa · 2016Article
- Evaluating a unique, specialist psychiatric genetic counseling clinic: uptake and impact.Clinical genetics · 2015Article
- The impact of participation in genetic research for families with cleft lip with and without cleft palate: a qualitative study.Journal of community genetics · 2014Article
- Adaptation to bipolar disorder and perceived risk to children: a survey of parents with bipolar disorder.BMC psychiatry · 2013Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
Abstract
No genetic tests are currently clinically available for serious mental illnesses such as schizophrenia and bipolar disorder. Rather, the full spectrum of genetic variants that confer susceptibility remain unknown, and estimates of probability of condition recurrence typically have the form of ranges rather than single absolute numbers. Genetic counselors have been shown to feel that the information that can be provided for patients with serious mental illness could be more confusing than helpful. However, how those with serious mental illness perceive this uncertainty remains unknown. So, to investigate this, individuals with serious mental illness participated in a psychiatric genetic counseling (GC) session and responded to a single open ended question about their reactions towards the uncertainty that they encountered in their GC session immediately and one month post-counseling (from which themes were identified), and completed the Genetic Counseling Satisfaction Scale immediately post-session (descriptive statistics applied). While some of the 37 participants were disappointed with the uncertainty, twice as many were unconcerned. Overall, responses from immediately and one month after GC were very similar; participants were very satisfied with, and found value in GC despite uncertainty, and four approaches to coping with uncertainty emerged. Ultimately, these findings offer insight into providing GC for those with serious mental illness, and potentially could be applied to other areas of GC where uncertainty lies, with downstream impact on GC practice and future research.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.