Evidence map›Paper›PMID 23603811›Full record

ArticleEnvironmental health perspectives2013

Residential proximity to methyl bromide use and birth outcomes in an agricultural population in California.

Alison Gemmill, Robert B Gunier, Asa Bradman, Brenda Eskenazi, Kim G Harley

Abstract read
In one paragraph

Article in Environmental health perspectives, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
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  5. Personal air sampling for pesticides in the California San Joaquin Valley.Journal of exposure science & environmental epidemiology · 2025
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors.

Alison GemmillDepartment of Demography, University of California, Berkeley, Berkeley, California 94704 , USA.
Robert B Gunier
Asa Bradman
Brenda Eskenazi
Kim G Harley

Funding

Project C: Epigenetic Effects of DDT/E and PBDEs on PubertyP01ES009605 · NIEHS · UNIVERSITY OF CALIFORNIA BERKELEY · PI ESKENAZI, BRENDA · 1999 to 2015
$11.2M
INTERDISCIPLINARY TRAINING IN DEMOGRAPHYT32HD007275 · NICHD · UNIVERSITY OF CALIFORNIA BERKELEY · PI FEEHAN, DENNIS MICHAEL · 1985 to 2025
$5.3M
NICHD NIH HHS HD07275NICHD NIH HHS T32 HD007275NIEHS NIH HHS P01 ES009605PHS HHS R82670901
6 · The paper itself

Abstract

backgroundMethyl bromide, a fungicide often used in strawberry cultivation, is of concern for residents who live near agricultural applications because of its toxicity and potential for drift. Little is known about the effects of methyl bromide exposure during pregnancy.

objectiveWe investigated the relationship between residential proximity to methyl bromide use and birth outcomes.

methodsParticipants were from the CHAMACOS (Center for the Health Assessment of Mothers and Children of Salinas) study (n = 442), a longitudinal cohort study examining the health effects of environmental exposures on pregnant women and their children in an agricultural community in northern California. Using data from the California Pesticide Use Reporting system, we employed a geographic information system to estimate the amount of methyl bromide applied within 5 km of a woman's residence during pregnancy. Multiple linear regression models were used to estimate associations between trimester-specific proximity to use and birth weight, length, head circumference, and gestational age.

resultsHigh methyl bromide use (vs. no use) within 5 km of the home during the second trimester was negatively associated with birth weight (β = -113.1 g; CI: -218.1, -8.1), birth length (β = -0.85 cm; CI: -1.44, -0.27), and head circumference (β = -0.33 cm; CI: -0.67, 0.01). These outcomes were also associated with moderate methyl bromide use during the second trimester. Negative associations with fetal growth parameters were stronger when larger (5 km and 8 km) versus smaller (1 km and 3 km) buffer zones were used to estimate exposure.

conclusionsResidential proximity to methyl bromide use during the second trimester was associated with markers of restricted fetal growth in our study.

Indexed as

AgricultureAdultBirth WeightCaliforniaFemaleFetal DevelopmentFetusHumansHydrocarbons, BrominatedLinear ModelsMaternal ExposurePregnancyHydrocarbons, Brominatedmethyl bromide

Identifiers

PMID23603811
PMCPMC3672911

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.