ArticleNature neuroscience2013
Segregation of cortical head direction cell assemblies on alternating θ cycles.
Article in Nature neuroscience, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 73 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
73 citing papers in PubMed, 128 citations in OpenAlex.
- Dorsoventral gradient of theta sweeps in the medial entorhinal cortex.Science advances · 2026Article
- Decoding Medial Entorhinal Cortical Dynamics Produces Planning-Like Alternations in Hippocampal theta Sequences.Hippocampus · 2026Article
- Path Integration in Alzheimer's Disease: Orientation, Movement, and Theta Rhythmicity.Annual review of neuroscience · 2026Review
- Review
- Relative phase of membrane potential theta oscillations between individual hippocampal neurons code space.bioRxiv : the preprint server for biology · 2025Article
- Allothetic and idiothetic spatial cues control the multiplexed theta phase coding of place cells.Nature neuroscience · 2025Article
- Theta Oscillons in Behaving Rats.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025Article
- Article
- Phase Precession Relative to Turning Angle in Theta-Modulated Head Direction Cells.Hippocampus · 2025Article
- A systems model of alternating theta sweeps via firing rate adaptation.Current biology : CB · 2025Article
- Navigation: Scanning your future path.Current biology : CB · 2025Article
- Unweaving the Cognitive Map: A Personal History.Hippocampus · 2025Review
- Development of the SPEAR Model: Separate Phases of Encoding and Retrieval Are Necessary for Storing Multiple Overlapping Associative Memories.Hippocampus · 2025Review
- Mental Time Travel: A Retrospective.Hippocampus · 2025Review
- Intrinsic Bipolar Head-Direction Cells in the Medial Entorhinal Cortex.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024Article
- Firing rate adaptation affords place cell theta sweeps, phase precession, and procession.eLife · 2024Article
- Comparison of head direction cell firing characteristics across thalamo-parahippocampal circuitry.Hippocampus · 2024Article
- The medial septum controls hippocampal supra-theta oscillations.Nature communications · 2023Article
- Septo-hippocampal dynamics and the encoding of space and time.Trends in neurosciences · 2023Review
- Convergence of location, direction, and theta in the rat anteroventral thalamic nucleus.iScience · 2023Article
13 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 1 country.
Funding
Abstract
High-level cortical systems for spatial navigation, including entorhinal grid cells, critically depend on input from the head direction system. We examined spiking rhythms and modes of synchrony between neurons participating in head direction networks for evidence of internal processing, independent of direct sensory drive, which may be important for grid cell function. We found that head direction networks of rats were segregated into at least two populations of neurons firing on alternate theta cycles (theta cycle skipping) with fixed synchronous or anti-synchronous relationships. Pairs of anti-synchronous theta cycle skipping neurons exhibited larger differences in head direction tuning, with a minimum difference of 40 degrees of head direction. Septal inactivation preserved the head direction signal, but eliminated theta cycle skipping of head direction cells and grid cell spatial periodicity. We propose that internal mechanisms underlying cycle skipping in head direction networks may be critical for downstream spatial computation by grid cells.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.