ReviewThe Journal of infection2013
The role of infection in Kawasaki syndrome.
Review in The Journal of infection, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 52 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
52 citing papers in PubMed, 2 syntheses or guidelines pooled it, 102 citations in OpenAlex.
- No causal association between gut microbiota and kawasaki disease: a two-sample mendelian randomization study.Pediatric research · 2025Pooled it
- Kawasaki Disease and the Use of the Rotavirus Vaccine in Children: A Systematic Review and Meta-Analysis.Frontiers in pharmacology · 2019Pooled it
- The gut microbiota and kawasaki disease: exploring the role of microbial dysbiosis and metabolites in pathogenesis and therapeutics.European journal of pediatrics · 2026Review
- Temporal trends in clinical and inflammatory features of Kawasaki disease across the COVID-19 pandemic: a single-center experience from Turkey.Frontiers in pediatrics · 2026Article
- Infectious mononucleosis complicated with Kawasaki disease: Two case reports and literature review.Pediatric investigation · 2025Article
- Cardio-Rheumatic Diseases: Inflammasomes Behaving Badly.International journal of molecular sciences · 2025Review
- Concurrent infections in children with Kawasaki disease: lessons learned over 26 years.Immunologic research · 2025Article
- Secular trend of Kawasaki disease and its correlation with viral activity in Taiwan: a nationwide population-based study.BMC public health · 2024Article
- Emerging evidence of microbial infection in causing systematic immune vasculitis in Kawasaki disease.Frontiers in microbiology · 2023Review
- Mycoplasma infection aggravates cardiac involvements in Kawasaki diseases: a retrospective study.Frontiers in immunology · 2023Article
- Article
- Evaluation of the association of birth order and group childcare attendance with Kawasaki disease using data from a nationwide longitudinal survey.Frontiers in pediatrics · 2023Article
- Heparin-Binding Protein: A Prognostic Biomarker Associated with Severe or Complicated Community-Acquired Pneumonia in Children.Journal of inflammation research · 2023Article
- Associations between the spatiotemporal distribution of Kawasaki disease and environmental factors: evidence supporting a multifactorial etiologic model.Scientific reports · 2021Article
- Kawasaki disease in an infant after administration of hexavalent vaccine.Saudi medical journal · 2021Article
- Clinical characteristics of Kawasaki disease and concurrent pathogens during isolation in COVID-19 pandemic.World journal of pediatrics : WJP · 2021Article
- Multisystem Inflammatory Syndrome in Children Related to SARS-CoV-2.Paediatric drugs · 2021Article
- Family Transmission of COVID-19 Including a Child with MIS-C and Acute Pancreatitis.International medical case reports journal · 2021Article
- Incidence of Kawasaki disease before and during the COVID-19 pandemic: a retrospective cohort study in Japan.BMJ paediatrics open · 2021Article
- Kawasaki Disease Complicated byCase reports in pediatrics · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesTo analyse the evidence suggesting a possible infectious origin of Kawasaki syndrome (KS).
methodsPubMed was searched for all of the studies published over the last 15 years using the key words "Kawasaki syndrome" or "mucocutaneous lymph node syndrome" and "infectious disease" or "genetics" or "vasculitis" or "pathogenesis".
resultsVarious levels of evidence support the hypothesis that KS is a complex disease triggered by an infection due to one or more pathogens. Viruses or bacteria may be the primum movens, although no specific infectious agent can be considered definitely etiological. A number of genetic polymorphisms have been identified in subjects with KS, but none of them can currently be considered a real marker of susceptibility.
conclusionsVarious data suggest that KS is intimately related to infectious diseases and that its clinical expression is influenced by predisposing genetic backgrounds, but our knowledge of the infectious agent(s) involved and the genetic characteristics of susceptible children remains only partial. Further studies are needed to address the many still open questions concerning the disease.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.