Evidence map›Paper›PMID 23602918›Full record

ArticleMedical image analysis2013

A three-dimensional finite element model of human atrial anatomy: new methods for cubic Hermite meshes with extraordinary vertices.

Matthew J Gonzales, Gregory Sturgeon, Adarsh Krishnamurthy, Johan Hake, René Jonas, Paul Stark, Wouter-Jan Rappel, Sanjiv M Narayan, Yongjie Zhang, W Paul Segars and 1 more

Abstract read
In one paragraph

Article in Medical image analysis, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed.

  1. Article
  2. Impact of Catheter Configuration on the Mapping of Atrial Fibrillation.Circulation. Arrhythmia and electrophysiology · 2026
    Article
  3. Article
  4. Article
  5. Forward-Solution Noninvasive Computational Arrhythmia Mapping: The VMAP Study.Circulation. Arrhythmia and electrophysiology · 2022
    Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Review
  15. Article
  16. Non-invasive, model-based measures of ventricular electrical dyssynchrony for predicting CRT outcomes.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2016
    Article
  17. Review
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Matthew J GonzalesDepartment of Bioengineering, University of California San Diego, La Jolla, CA, USA.
Gregory Sturgeon
Adarsh Krishnamurthy
Johan Hake
René Jonas
Paul Stark
Wouter-Jan Rappel
Sanjiv M Narayan
Yongjie Zhang
W Paul Segars
Andrew D McCulloch

Funding

MEDICAL SCIENTIST TRAINING PROGRAMT32GM007198 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI CHI, NEIL C, INSEL, PAUL A · 1985 to 2024
$29.3M
National Biomedical Computation Resource - Competitive Revision SupplementP41GM103426 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI AMARO, ROMMIE E · 2012 to 2019
$14.0M
The Virtual Physiological Rat ProjectP50GM094503 · NIGMS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI BEARD, DANIEL A · 2011 to 2015
$11.6M
CARDIOVASCULAR SURGERY/BIOENGINEERING TRAININGT32HL007089 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI CHIEN, SHU · 1985 to 2009
$9.3M
The Dynamics of Human Atrial FibrillationR01HL083359 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Sanjiv M Narayan · 2008 to 2026
$7.9M
Training in Multi-Scale Analysis of Biological Structure and FunctionT32EB009380 · NIBIB · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Andrew D. McCulloch, Padmini Rangamani · 2009 to 2026
$4.8M
Integrative Bioengineering of Heart, Vessels, and BloodT32HL105373 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI CHIEN, SHU, INTAGLIETTA, MARCOS · 2010 to 2019
$3.6M
Multi-scale Systems Model of Murine Heart FailureR01HL105242 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI BERS, DONALD M, MCCULLOCH, ANDREW D. · 2012 to 2016
$3.5M
Multi-Scale Model of the Human Heart for Imaging ResearchR01HL091036 · NHLBI · DUKE UNIVERSITY · PI SEGARS, WILLIAM P · 2009 to 2012
$2.1M
The Maintenance of Human Atrial FibrillationK24HL103800 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI NARAYAN, SANJIV M · 2010 to 2019
$1.9M
Multi-Scale Modeling of the Failing Heart for Cardiac Rysynchronization TherapyR01HL096544 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI MCCULLOCH, ANDREW D. · 2009 to 2013
$1.8M
Modeling and analysis of the mechanochemical processes that govern clathrin-mediated endocytosisR01GM132106 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI RANGAMANI, PADMINI · 2020 to 2024
$1.5M
NHLBI NIH HHS 1 K24 HL103800NHLBI NIH HHS 1 R01 HL083359NHLBI NIH HHS 1 R01 HL96544NHLBI NIH HHS 1 RO1 HL091036NHLBI NIH HHS 1 T32 HL105373NHLBI NIH HHS 5 T32 HL007089NHLBI NIH HHS K24 HL103800NHLBI NIH HHS R01 HL083359NHLBI NIH HHS R01 HL091036NHLBI NIH HHS R01 HL096544NHLBI NIH HHS R01 HL105242NHLBI NIH HHS T32 HL007089NHLBI NIH HHS T32 HL105373NIBIB NIH HHS 1 T32 EB009380NIBIB NIH HHS T32 EB009380NIGMS NIH HHS 8 P41 GM103426NIGMS NIH HHS P41 GM103426NIGMS NIH HHS P50 GM094503NIGMS NIH HHS R01 GM132106NIGMS NIH HHS T32 GM007198
6 · The paper itself

Abstract

High-order cubic Hermite finite elements have been valuable in modeling cardiac geometry, fiber orientations, biomechanics, and electrophysiology, but their use in solving three-dimensional problems has been limited to ventricular models with simple topologies. Here, we utilized a subdivision surface scheme and derived a generalization of the "local-to-global" derivative mapping scheme of cubic Hermite finite elements to construct bicubic and tricubic Hermite models of the human atria with extraordinary vertices from computed tomography images of a patient with atrial fibrillation. To an accuracy of 0.6 mm, we were able to capture the left atrial geometry with only 142 bicubic Hermite finite elements, and the right atrial geometry with only 90. The left and right atrial bicubic Hermite meshes were G1 continuous everywhere except in the one-neighborhood of extraordinary vertices, where the mean dot products of normals at adjacent elements were 0.928 and 0.925. We also constructed two biatrial tricubic Hermite models and defined fiber orientation fields in agreement with diagrammatic data from the literature using only 42 angle parameters. The meshes all have good quality metrics, uniform element sizes, and elements with aspect ratios near unity, and are shared with the public. These new methods will allow for more compact and efficient patient-specific models of human atrial and whole heart physiology.

Indexed as

AlgorithmsModels, AnatomicModels, CardiovascularAgedComputer SimulationFinite Element AnalysisHeart AtriaHumansImaging, Three-DimensionalMaleRadiographic Image Interpretation, Computer-AssistedReproducibility of ResultsSensitivity and SpecificityTomography, X-Ray Computed

Identifiers

PMID23602918
PMCPMC3660421

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.