Evidence map›Paper›PMID 23601497›Full record

Trial reportThe Journal of pediatrics2013

The impact of succimer chelation on blood cadmium in children with background exposures: a randomized trial.

Yang Cao, Aimin Chen, Matteo Bottai, Kathleen L Caldwell, Walter J Rogan

Open access · greenAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in The Journal of pediatrics, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
1.7field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 12 citations in OpenAlex.

  1. Toxic metals in tissues of fishes from the Black Sea and associated human health risk exposure.Environmental science and pollution research international · 2017
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 2 countries.

Yang CaoUnit of Biostatistics, Division of Epidemiology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.
Aimin Chen
Matteo Bottai
Kathleen L Caldwell
Walter J Rogan
Karolinska Institutet · SECenters for Disease Control and Prevention · USNational Institute of Environmental Health Sciences · USUniversity of Cincinnati Medical Center · US

Funding

REPRODUCTIVE AND DEVELOPMENTAL TOXICOLOGY RESEARCHP30ES006096 · NIEHS · UNIVERSITY OF CINCINNATI · PI PINNEY, SUSAN MENGEL · 1992 to 2022
$35.4M
Human developmental toxicity of metal mixture exposure from e-waste recyclingRC4ES019755 · NIEHS · UNIVERSITY OF CINCINNATI · PI CHEN, AIMIN · 2010 to 2010
$1.7M
Toxicity Of Lead In Children--Clinical TrialZIAES043011 · NIEHS · NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES · PI ROGAN, WALTER · 2009 to 2014
$1.5M
Intramural NIH HHS ZIA ES043011NIEHS NIH HHS P30 ES006096NIEHS NIH HHS RC4 ES019755
6 · The paper itself

Abstract

Succimer lowers blood lead concentrations in children, and the structure of succimer chelates of lead and cadmium are similar. Using blood samples from a randomized trial of succimer for lead poisoning, however, we found that succimer did not lower blood cadmium in children with background exposure.

Indexed as

Chelation TherapyCadmiumChelating AgentsChildEnvironmental ExposureHumansLead PoisoningSuccimerCadmiumChelating AgentsSuccimerLimit of detectionLOD

Identifiers

PMID23601497
PMCPMC3723771
OpenAlexW1982468917

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.