ReviewDiagnostic microbiology and infectious disease2013
Clinical and economical impact of multiplex respiratory virus assays.
Review in Diagnostic microbiology and infectious disease, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
33 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Rapid Molecular Tests for Influenza, Respiratory Syncytial Virus, and Other Respiratory Viruses: A Systematic Review of Diagnostic Accuracy and Clinical Impact Studies.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2019Pooled it
- Diagnostic Accuracy of Rapid Antigen Detection Tests for Respiratory Syncytial Virus Infection: Systematic Review and Meta-analysis.Journal of clinical microbiology · 2015Pooled it
- Biosensors as transformative tools for multiplex detection of respiratory viral pathogens.Archives of microbiology · 2026Review
- Acute Respiratory Viral Infections Among Adult Patients in Edirne, Turkey.Tropical medicine and infectious disease · 2025Article
- Prevalence and clinical course of upper airway respiratory virus infection in critically ill patients with hematologic malignancies.PloS one · 2021Observational
- Causes and consequences of fever during pregnancy: A retrospective study in a gynaecological emergency department.Journal of gynecology obstetrics and human reproduction · 2020Article
- Evaluation of a multiplex PCR assay for detection of respiratory viruses and Mycoplasma pneumoniae in oropharyngeal swab samples from outpatients.Journal of clinical laboratory analysis · 2020Article
- Accuracy of diagnostic tests for respiratory syncytial virus infection within a paediatric hospital population in Kilifi County, Kenya.Wellcome open research · 2020Article
- Molecular Diagnosis of Pneumonia Using Multiplex Real-Time PCR Assay RespiFinder® SMART 22 FAST in a Group of Moroccan Infants.Advances in virology · 2020Article
- Cost-Effective Respiratory Virus Testing.Journal of clinical microbiology · 2019Review
- Prevalence and characteristics of acute respiratory virus infections in pediatric cancer patients.Journal of medical virology · 2019Article
- Contribution of the FilmArray Respiratory Panel in the management of adult and pediatric patients attending the emergency room during 2015-2016 influenza epidemics: An interventional study.International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases · 2019Article
- Respiratory Viral Infection: An Underappreciated Cause of Acute Febrile Illness Admissions in Southern Sri Lanka.The American journal of tropical medicine and hygiene · 2019Article
- Clinical Performance of the AllplexTM Respiratory Panel 1 Test Compared to SimplexaTM Flu A/B and RSV for Detection of Influenza Virus and Respiratory Syncytial Virus Infection Including Their Subtyping.Medical principles and practice : international journal of the Kuwait University, Health Science Centre · 2019Article
- Review
- Epidemiology and seasonality of acute respiratory infections in hospitalized children over four consecutive years (2012-2016).Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology · 2018Article
- Multicenter Clinical Evaluation of the Luminex Aries Flu A/B & RSV Assay for Pediatric and Adult Respiratory Tract Specimens.Journal of clinical microbiology · 2017Article
- Performance evaluation of direct fluorescent antibody, Focus Diagnostics Simplexa™ Flu A/B & RSV and multi-parameter customized respiratory Taqman® array card in immunocompromised patients.Journal of virological methods · 2017Article
- Necessity to critically review the automatic results of the Xpert Flu assay.Diagnostic microbiology and infectious disease · 2017Article
- Antimicrobial Stewardship: How the Microbiology Laboratory Can Right the Ship.Clinical microbiology reviews · 2017Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
During the last decade, a variety of molecular assays targeting respiratory viruses have been developed and commercialized. Therefore, multiplex PCR are increasingly used in everyday clinical practice. This improves our understanding of respiratory virus epidemiology and enhances our concerns about their clinical impact in specific patient populations. However, questions remain regarding cost-effectiveness of performing these diagnostic tests in routine and their real impact on patient care. This article will review available data and highlight unresolved questions about cost-effectiveness, infection control, clinical utility and public health impact of multiplex respiratory virus assays.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.