ArticleBiophysical journal2013
Low frequency entrainment of oscillatory bursts in hair cells.
Article in Biophysical journal, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed.
- Neural control and innate self-tuning of the hair cell's active process.Biophysical journal · 2024Article
- Criticality and chaos in auditory and vestibular sensing.Scientific reports · 2024Article
- Complex dynamics of hair bundle of auditory nervous system (I): spontaneous oscillations and two cases of steady states.Cognitive neurodynamics · 2022Article
- Chaotic Dynamics Enhance the Sensitivity of Inner Ear Hair Cells.Scientific reports · 2019Article
- Active Biomechanics of Sensory Hair Bundles.Cold Spring Harbor perspectives in medicine · 2019Review
- Chaotic Dynamics of Inner Ear Hair Cells.Scientific reports · 2018Article
- Homeostatic enhancement of sensory transduction.Proceedings of the National Academy of Sciences of the United States of America · 2017Article
- High-order synchronization of hair cell bundles.Scientific reports · 2016Article
- Frequency locking in auditory hair cells: Distinguishing between additive and parametric forcing.Europhysics letters · 2016Article
- Identification of Bifurcations from Observations of Noisy Biological Oscillators.Biophysical journal · 2016Article
- Control of a hair bundle's mechanosensory function by its mechanical load.Proceedings of the National Academy of Sciences of the United States of America · 2015Article
- Phase-locked spiking of inner ear hair cells and the driven noisy Adler equation.Interface focus · 2014Article
- Mechanical overstimulation of hair bundles: suppression and recovery of active motility.PloS one · 2013Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
Abstract
Sensitivity of mechanical detection by the inner ear is dependent upon a highly nonlinear response to the applied stimulus. Here we show that a system of differential equations that support a subcritical Hopf bifurcation, with a feedback mechanism that tunes an internal control parameter, captures a wide range of experimental results. The proposed model reproduces the regime in which spontaneous hair bundle oscillations are bistable, with sporadic transitions between the oscillatory and the quiescent state. Furthermore, it is shown, both experimentally and theoretically, that the application of a high-amplitude stimulus to the bistable system can temporarily render it quiescent before recovery of the limit cycle oscillations. Finally, we demonstrate that the application of low-amplitude stimuli can entrain bundle motility either by mode-locking to the spontaneous oscillation or by mode-locking the transition between the quiescent and oscillatory states.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.