ReviewJournal of medicine and life2013
Gingival crevicular fluid as a periodontal diagnostic indicator- II: Inflammatory mediators, host-response modifiers and chair side diagnostic aids.
Review in Journal of medicine and life, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
32 citing papers in PubMed, 49 citations in OpenAlex.
- Inflammatory parameters and color alterations of dental bleaching in patients wearing fixed orthodontic appliance: a randomized clinical trial.BMC oral health · 2023Trial
- Hydrogen peroxide-based products alter inflammatory and tissue damage-related proteins in the gingival crevicular fluid of healthy volunteers: a randomized trial.Scientific reports · 2019Trial
- Comparative proteomic analysis of gingival crevicular fluid and periodontal tissue: revealing clinical potential.Clinical proteomics · 2026Article
- Application of the miRNAs as biomarkers and therapeutic strategies in periodontal inflammation.Frontiers in pharmacology · 2026Review
- Periodontal ligament stem cells in tissue remodeling: from mechanical forces to inflammatory signals.Stem cell research & therapy · 2025Review
- Natural and induced immune responses in oral cavity and saliva.BMC immunology · 2025Review
- Study of Periodontal Bacteria in Diabetic Wistar Rats: Assessing the Anti-Inflammatory Effects of Carvacrol and Magnolol Hydrogels.Biomedicines · 2024Article
- A Study of the Association between Primary Oral Pathologies (Dental Caries and Periodontal Diseases) Using Synchrotron Molecular FTIR Spectroscopy in View of the Patient's Personalized Clinical Picture (Demographics and Anamnesis).International journal of molecular sciences · 2024Article
- Interleukin 1 beta and its association with the periodontal health of pregnant women.Journal of Taibah University Medical Sciences · 2023Article
- Nociceptor-Macrophage Interactions in Apical Periodontitis: How Biomolecules Link Inflammation with Pain.Biomolecules · 2023Review
- IgA Levels among Type 2 Diabetic and Non-Diabetic Patients with Periodontitis: A Prospective Clinical Study.European journal of dentistry · 2023Article
- Mechanisms Underlying the Suppression of IL-1β Expression by Magnesium Hydroxide Nanoparticles.Biomedicines · 2023Article
- Can the Correlation of Periodontopathies with Gastrointestinal Diseases Be Used as Indicators in Severe Colorectal Diseases?Biomedicines · 2023Article
- Periodontal Health and Disease in the Context of Systemic Diseases.Mediators of inflammation · 2023Review
- Immunoglobulin Disorders and the Oral Cavity: A Narrative Review.Journal of clinical medicine · 2022Review
- Fixed Prosthetic Restorations and Periodontal Health: A Narrative Review.Journal of functional biomaterials · 2022Review
- Non-Surgical Periodontal Therapy Could Improve the Periodontal Inflammatory Status in Patients with Periodontitis and Chronic Hepatitis C.Journal of clinical medicine · 2021Article
- Metabolic Disturbance and Th17/Treg Imbalance Are Associated With Progression of Gingivitis.Frontiers in immunology · 2021Observational
- Infection ofCells · 2020Article
- IL-1 Superfamily Members and Periodontal Diseases.Journal of dental research · 2020Review
Corrections and comments
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Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
There has been a steady growing trend during the last few decades to develop tools to monitor periodontitis, in the field of oral disease diagnosis. Since GCF has the chance of being closely approximated to the periodontal tissues where periodontal disease begins, it seems to provide more information than markers in saliva. In response to bacterial infection, host production of inflammatory mediators, may be the trigger for periodontal disease progression. Existing paradigms in the biology of periodontitis have supported the detection of elevated levels of these mediators in GCF. This article is the Part II of the review that deals with inflammatory mediators and host-response modifiers as the potential biomarkers present in gingival crevicular fluid (GCF) and the chair side point-of-care diagnostic aids applicable to monitor periodontal inflammation.
Indexed as
Identifiers
23599812PMC3624651W1551182024What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.