Evidence map›Paper›PMID 23599743›Full record

ArticleExperimental and therapeutic medicine2013

An altered expression of genes involved in the regulation of ion channels in atrial myocytes is correlated with the risk of atrial fibrillation in patients with heart failure.

Mei Gao, Jiangrong Wang, Zhongsu Wang, Yong Zhang, Hui Sun, Xinxing Xie, Yinglong Hou

Open access · diamondAbstract read
In one paragraph

Article in Experimental and therapeutic medicine, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.0field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

  1. Network Pharmacology and Pharmacological Mechanism of CV-3 in Atrial Fibrillation.Evidence-based complementary and alternative medicine : eCAM · 2022
    Article
  2. Review
  3. Remodeling of Kv1.5 channel in right atria from Han Chinese patients with atrial fibrillation.Medical science monitor : international medical journal of experimental and clinical research · 2015
    Article
  4. Atrial fibrillation and heart failure: cause or effect?Current heart failure reports · 2014
    Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Mei GaoDepartment of Cardiology, Shandong Provincial Qianfoshan Hospital, Shandong University, Jinan, P.R. China.
Jiangrong Wang
Zhongsu Wang
Yong Zhang
Hui Sun
Xinxing Xie
Yinglong Hou
Shandong Provincial QianFoShan Hospital · CNShandong University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The aim of this study was to investigate the correlation between the altered expression of genes involved in the regulation of ion channels in atrial myocytes and the risk of atrial fibrillation (AF) in patients with heart failure (HF). Right atrial appendages were obtained from 18 HF patients and 18 patients with normal cardiac functions who had undergone surgery. The mRNA expression levels of Kv4.3α, KvLQT1, Kv1.5, L-Caα

Indexed as

atrial fibrillationgene expressionheart failureion channel

Identifiers

PMID23599743
PMCPMC3628869
OpenAlexW1995165054

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.