Evidence map›Paper›PMID 23599620›Full record

ReviewWorld journal of gastroenterology2013

Clinical application of microRNA in gastric cancer in Eastern Asian area.

Ming Gao, Hao Yin, Zhe-Wei Fei

Open access · hybridAbstract readReview
In one paragraph

Review in World journal of gastroenterology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.0field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. [miR-449a/b negatively regulates E2F1 to suppress proliferation of gastric cancer cells].Nan fang yi ke da xue xue bao = Journal of Southern Medical University · 2020
    Article
  6. Article
  7. MiR-1236-3p serves as a new diagnostic and prognostic biomarker for gastric cancer.Cancer biomarkers : section A of Disease markers · 2019
    Article
  8. Article
  9. Evaluation of altered expression ofJournal of gastrointestinal oncology · 2018
    Article
  10. Role of microRNA-7 in digestive system malignancy.World journal of gastrointestinal oncology · 2016
    Review
  11. Review
  12. Review
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Ming GaoXin Hua Hospital-Chongming, Shanghai Jiao Tong University School of Medicine, Shanghai 202150, China.
Hao Yin
Zhe-Wei Fei
XinHua Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Recent research has shown that microRNA (miRNA), which is involved in almost every step of gastric carcinogenesis, has broad prospective application in diagnosis and therapy of gastric carcinoma. Eastern Asia (South Korea, Japan and China) has the highest incidence of gastric cancer in the world. There were 988,000 new cases of gastric cancer worldwide and 736,000 deaths in 2008. Approximately 60% of the cases of gastric cancer are found in East Asia (mainly China). We herein provide a brief review of the clinical applications of miRNA, which include the following aspects: (1) miRNA may serve as a potential new generation of tumor markers; (2) a complete miRNA expression profile is highly specific, can reflect the evolutionary lineage and differentiation of tumors, and be used to carry out diversity analysis; (3) detecting specific miRNA expression in peripheral blood will become a new method for diagnosis of gastric cancer; (4) miRNA can predict prognosis of gastric cancer; (5) miRNA has predictive value in determining chemotherapy and radiotherapy resistance; and (6) miRNA could be a type of innovative drug. Finally, we focus on assessing the value of miRNA from laboratory to clinical application and the challenges it faces in East Asia.

Indexed as

Area Under CurveBiomarkers, TumorChinaDrug Resistance, NeoplasmGene Expression ProfilingHumansJapanMicroRNAsPrognosisRepublic of KoreaStomach NeoplasmsBiomarkers, TumorMicroRNAsClinical applicationEastern AsiaGastric cancermicroRNAPrognosis

Identifiers

PMID23599620
PMCPMC3623978
OpenAlexW1977357666

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.