Evidence map›Paper›PMID 23599225›Full record

ArticleJournal of the American Medical Informatics Association : JAMIA2013

Relationship between medication event rates and the Leapfrog computerized physician order entry evaluation tool.

Alexander A Leung, Carol Keohane, Stuart Lipsitz, Eyal Zimlichman, Mary Amato, Steven R Simon, Michael Coffey, Nathan Kaufman, Bismarck Cadet, Gordon Schiff and 2 more

Open access · bronzeAbstract readEvaluation Study
In one paragraph

Article in Journal of the American Medical Informatics Association : JAMIA, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 1 pooled it
4.7field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 1 synthesis or guideline pooled it, 30 citations in OpenAlex.

  1. Pooled it
  2. Trial
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  16. National trends in safety performance of electronic health record systems in children's hospitals.Journal of the American Medical Informatics Association : JAMIA · 2017
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  17. NCPDP recommendations for dose accumulation monitoring in the inpatient setting: Acetaminophen case model, version 1.0.American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists · 2016
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  18. Review
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Alexander A LeungDivision of General Internal Medicine and Primary Care, Brigham and Women's Hospital, Boston, Massachusetts 02120-1613, USA.
Carol Keohane
Stuart Lipsitz
Eyal Zimlichman
Mary Amato
Steven R Simon
Michael Coffey
Nathan Kaufman
Bismarck Cadet
Gordon Schiff
Diane L Seger
David W Bates
Brigham and Women's Hospital · USMass General Brigham · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThe Leapfrog CPOE evaluation tool has been promoted as a means of monitoring computerized physician order entry (CPOE). We sought to determine the relationship between Leapfrog scores and the rates of preventable adverse drug events (ADE) and potential ADE. MATERIALS AND

methodsA cross-sectional study of 1000 adult admissions in five community hospitals from October 1, 2008 to September 30, 2010 was performed. Observed rates of preventable ADE and potential ADE were compared with scores reported by the Leapfrog CPOE evaluation tool. The primary outcome was the rate of preventable ADE and the secondary outcome was the composite rate of preventable ADE and potential ADE.

resultsLeapfrog performance scores were highly related to the primary outcome. A 43% relative reduction in the rate of preventable ADE was predicted for every 5% increase in Leapfrog scores (rate ratio 0.57; 95% CI 0.37 to 0.88). In absolute terms, four fewer preventable ADE per 100 admissions were predicted for every 5% increase in overall Leapfrog scores (rate difference -4.2; 95% CI -7.4 to -1.1). A statistically significant relationship between Leapfrog scores and the secondary outcome, however, was not detected. DISCUSSION: Our findings support the use of the Leapfrog tool as a means of evaluating and monitoring CPOE performance after implementation, as addressed by current certification standards.

conclusionsScores from the Leapfrog CPOE evaluation tool closely relate to actual rates of preventable ADE. Leapfrog testing may alert providers to potential vulnerabilities and highlight areas for further improvement.

Indexed as

Drug-Related Side Effects and Adverse ReactionsMedical Order Entry SystemsAdultHospitals, CommunityHumansMassachusettsMedication Errorsclinical decision supportcomputerized physician order entryLeapfrogmedication safety

Identifiers

PMID23599225
PMCPMC3715361
OpenAlexW51696933

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.