ArticleExperimental biology and medicine (Maywood, N.J.)2013
Directed neural differentiation of induced pluripotent stem cells from non-human primates.
Article in Experimental biology and medicine (Maywood, N.J.), 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
9 citing papers in PubMed.
- Infrastructure to Support Accrual of Older Adults to National Cancer Institute Clinical Trials.Journal of the National Cancer Institute. Monographs · 2022Article
- Optimization of Differentiation of Nonhuman Primate Pluripotent Cells Using a Combinatorial Approach.Methods in molecular biology (Clifton, N.J.) · 2019Article
- Standards for Deriving Nonhuman Primate-Induced Pluripotent Stem Cells, Neural Stem Cells and Dopaminergic Lineage.International journal of molecular sciences · 2018Article
- Induced Pluripotent Stem Cell-Derived Dopaminergic Neurons from Adult Common Marmoset Fibroblasts.Stem cells and development · 2017Article
- Overcoming barriers to reprogramming and differentiation in nonhuman primate induced pluripotent stem cells.Primate biology · 2017Article
- Differentiation and Characterization of Dopaminergic Neurons From Baboon Induced Pluripotent Stem Cells.Stem cells translational medicine · 2016Article
- Marmoset induced pluripotent stem cells: Robust neural differentiation following pretreatment with dimethyl sulfoxide.Stem cell research · 2015Article
- Large-scale polymorphism discovery in macaque G-protein coupled receptors.BMC genomics · 2013Article
- Patient-specific induced pluripotent stem cells in neurological disease modeling: the importance of nonhuman primate models.Stem cells and cloning : advances and applications · 2013Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
Induced pluripotent stem cells (iPS cells) are important for the future development of regenerative medicine involving autologous cell therapy. Before autologous cell therapy can be applied to human patients, suitable animal models must be developed, and in this context non-human primate models are critical. We previously characterized several lines of marmoset iPS cells derived from newborn skin fibroblasts. In the present studies, we explored methods for the directed differentiation of marmoset iPS cells in the neuroectodermal lineage. In this process we used an iterative process in which combinations of small molecules and protein factors were tested for their effects on mRNA levels of genes that are markers for the neuroectodermal lineage. This iterative process identified combinations of chemicals/factors that substantially improved the degree of marker gene expression over the initially tested combinations. This approach should be generally valuable in the directed differentiation of pluripotent cells for experimental cell therapy.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.