ArticleEye (London, England)2013
Outbreak of microsporidial keratoconjunctivitis with rugby sport due to soil exposure.
Article in Eye (London, England), 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed, 39 citations in OpenAlex.
- Clinical profile of microsporidial keratoconjunctivitis in healthy individuals of China -new species and neglected risk factors.Journal of ophthalmic inflammation and infection · 2026Article
- PI3K/Akt Signaling as a Potential Therapeutic Target for Reducing Inflammation and Corneal Stromal Injury in Microsporidial Stromal Keratitis.Investigative ophthalmology & visual science · 2026Article
- Weather, Air Pollution, and Seasonality: Predictors of Pathogen-Associated Conjunctivitis Outbreaks in Kathmandu Valley, Nepal.The American journal of tropical medicine and hygiene · 2025Article
- Clinical characteristics, progression patterns and treatment outcomes in microsporidial keratoconjunctivitis: a prospective study in Thailand.International ophthalmology · 2024Article
- Case Report: The Use of In Vivo Confocal Microscopy for Diagnosis and Monitoring in a Rare Case of Ancaliia algerae Microsporidial Keratitis in New South Wales, Australia.The American journal of tropical medicine and hygiene · 2024Article
- Microsporidial keratoconjunctivitis - first outbreak in Japan.BMC infectious diseases · 2023Observational
- Metagenomic sequencing for investigation of a national keratoconjunctivitis outbreak, Israel, 2022.Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin · 2023Article
- Current Therapy and Therapeutic Targets for Microsporidiosis.Frontiers in microbiology · 2022Review
- Article
- Sequelae of microsporidial keratoconjunctivitis and its management.Indian journal of ophthalmology · 2021Article
- Temporal trend of microsporidial keratoconjunctivitis and correlation with environmental and air pollution factors in India.Indian journal of ophthalmology · 2021Article
- A Narrative Review of Microsporidial Infections of the Cornea.Ophthalmology and therapy · 2020Review
- Microsporidial keratitis retrospectively diagnosed by ultrastructural study of formalin-fixed paraffin-embedded corneal tissue: a case report.Annals of clinical microbiology and antimicrobials · 2019Article
- Importance of clinical signs leading to the diagnosis in a case of microbiological smear negative ocular microsporidiosis.BMJ case reports · 2019Article
- Case Report: Ocular Microsporidiosis: Case in a Patient Returning from India and Review of the Literature.The American journal of tropical medicine and hygiene · 2018Review
- A DNA dot hybridization model for molecular diagnosis of parasitic keratitis.Molecular vision · 2017Article
- Parasitic keratitis - An under-reported entity.Tropical parasitologyArticle
- Simple Congenital Hamartoma of the Retinal Pigment Epithelium.Journal of ophthalmic & vision researchArticle
- Microsporidial Keratoconjunctivitis.Journal of ophthalmic & vision researchArticle
Corrections and comments
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Authors and funding
6 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimsTo investigate a cluster of microsporidial keratoconjunctivitis in 33 eyes of 25 previously healthy paediatric and teenage individuals after a rugby match.
methodsAn observational case series was reported. Analysis of medical record of patients with microsporidial keratoconjunctivitis, who presented within May 2012, was performed. All patients were treated by a single ophthalmologist with a standardized topical regime, including a fluoroquinolone (moxifloxacin) and an antiseptic (Brolene or Desomedine). Five eyes received corneal scrapings.
resultsThe mean age was 13.36 years (range 5-16). All patients have participated in a rugby match on 21-22 April 2012. The onset of symptoms ranged from 10 to 30 days post exposure. All eyes had multiple superficial coarse punctate keratitis. Four (12%) eyes presented with keratic precipitates. One (3%) eye had intraocular pressure of 27 mm Hg. Microscopic examination of corneal scrapings with modified trichrome or calcofluor white (CFW) fluorescent staining was unremarkable but subsequent PCR test was positive for the small subunit rRNA gene of Vittaforma corneae in three out of five eyes. Sequencing of the PCR product of 1150 bp showed 96-100% identity with the Indian or Singaporean strains of V. corneae. After treatment, all eyes healed without sequel.
conclusionsThe first outbreak of microsporidial keratoconjunctivitis in paediatric and teenage individuals with a rugby match is reported. A standardized topical regime, including a fluoroquinolone (moxifloxacin) and an antiseptic (Brolene or Desomedine), seems to be safe and effective, and requires validation in future treatment trials.
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