SynthesisAmerican journal of public health2013
Clinical uncertainties, health service challenges, and ethical complexities of HIV "test-and-treat": a systematic review.
Synthesis in American journal of public health, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
24 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Housing Status, Medical Care, and Health Outcomes Among People Living With HIV/AIDS: A Systematic Review.American journal of public health · 2016Pooled it
- Clinical uncertainties, health service challenges, and ethical complexities of HIV "test-and-treat": a systematic review.American journal of public health · 2013Pooled it
- Trial
- Provider and Patient Perspectives of Rapid ART Initiation and Streamlined HIV Care: Qualitative Insights From Eastern African Communities.Journal of the International Association of Providers of AIDS CareTrial
- Determinants of loss to follow-up among people living with HIV receiving antiretroviral therapy in a universal test and treat setting: A retrospective cohort study in Nepal.Public health in practice (Oxford, England) · 2025Article
- Network analysis of comorbid mental health disorders among people with HIV in the All of Us Research Program.Research square · 2025Article
- Multilevel determinants of antiretroviral therapy initiation and retention in the test-and-treat era of Nepal: a qualitative study.BMC health services research · 2024Article
- Consistency of Multi-Month Antiretroviral Therapy Dispensing and Association with Viral Load Coverage among Pediatric Clients Living with HIV in Mozambique.Tropical medicine and infectious disease · 2024Article
- Health provider perspectives on the implementation of the same-day-ART initiation policy in the Gauteng province of South Africa.Health research policy and systems · 2021Article
- The development of Maisha, a video-assisted counseling intervention to address HIV stigma at entry into antenatal care in Tanzania.Evaluation and program planning · 2020Article
- What do the Universal Test and Treat trials tell us about the path to HIV epidemic control?Journal of the International AIDS Society · 2020Article
- Same-day antiretroviral treatment (ART) initiation and associated factors among HIV positive people in Northwest Ethiopia: baseline characteristics of prospective cohort.Archives of public health = Archives belges de sante publique · 2020Article
- Population uptake and effectiveness of test-and-treat antiretroviral therapy guidelines for preventing the global spread of HIV: an ecological cross-national analysis.HIV medicine · 2019Article
- Capturing HIV Incidence Among MSM Through At-Home and Self-reported Facility-based Testing.Journal of acquired immune deficiency syndromes (1999) · 2017Article
- HIV testing experiences and their implications for patient engagement with HIV care and treatment on the eve of 'test and treat': findings from a multicountry qualitative study.Sexually transmitted infections · 2017Article
- Patient-reported barriers and facilitators to antiretroviral adherence in sub-Saharan Africa.AIDS (London, England) · 2017Review
- Economic Evaluation of Community-Based HIV Prevention Programs in Ontario: Evidence of Effectiveness in Reducing HIV Infections and Health Care Costs.AIDS and behavior · 2016Article
- HIV Self-Testing: a Review of Current Implementation and Fidelity.Current HIV/AIDS reports · 2016Review
- Trauma-Informed Social Policy: A Conceptual Framework for Policy Analysis and Advocacy.American journal of public health · 2016Article
- Bridging barriers to clinic-based HIV testing with new technology: translating self-implemented testing for African American youth.Translational behavioral medicine · 2015Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
Despite the HIV "test-and-treat" strategy's promise, questions about its clinical rationale, operational feasibility, and ethical appropriateness have led to vigorous debate in the global HIV community. We performed a systematic review of the literature published between January 2009 and May 2012 using PubMed, SCOPUS, Global Health, Web of Science, BIOSIS, Cochrane CENTRAL, EBSCO Africa-Wide Information, and EBSCO CINAHL Plus databases to summarize clinical uncertainties, health service challenges, and ethical complexities that may affect the test-and-treat strategy's success. A thoughtful approach to research and implementation to address clinical and health service questions and meaningful community engagement regarding ethical complexities may bring us closer to safe, feasible, and effective test-and-treat implementation.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.