ArticleThe world journal of men's health2012
Antipsychotic-induced sexual dysfunction and its management.
Article in The world journal of men's health, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
31 citing papers in PubMed, 2 syntheses or guidelines pooled it, 77 citations in OpenAlex.
- Sexual dysfunction among people with mental illness in Africa: A systematic review and meta-analysis study.PloS one · 2024Pooled it
- A systematic review and meta-analysis of the association between clozapine and norclozapine serum levels and peripheral adverse drug reactions.Psychopharmacology · 2021Pooled it
- Erotic stimulus processing under amisulpride and reboxetine: a placebo-controlled fMRI study in healthy subjects.The international journal of neuropsychopharmacology · 2014Trial
- Sexual function concerns and attitudes toward discussing them with psychiatrists among psychiatric outpatients in Japan: a cross-sectional study.BMC psychiatry · 2026Article
- Sexual dysfunction associated with antidepressants and antipsychotics: a structured narrative review of mechanisms, assessment, and personalized management.Frontiers in psychiatry · 2026Review
- Male sexual dysfunction associated with TNF-α inhibitors: an indication-stratified global pharmacovigilance analysis.Frontiers in pharmacology · 2026Article
- Eros Unleashed: A Case Series of Cariprazine-induced Hypersexuality.Indian journal of psychological medicine · 2025Article
- Insufficient correctness of package inserts for psychotropic drugs in Germany.Naunyn-Schmiedeberg's archives of pharmacology · 2025Article
- Article
- Sexually transmitted infections, sexual life and risk behaviours of people living with schizophrenia: systematic review and meta-analysis.BJPsych open · 2024Review
- Article
- The atypical antipsychotics and sexual dysfunction: a pharmacovigilance-pharmacodynamic study.Frontiers in pharmacology · 2024Article
- Efficacy and Tolerance of Antipsychotics Used for the Treatment of Patients Newly Diagnosed with Schizophrenia: A Systematic Review and Meta-Analysis.Pharmacy (Basel, Switzerland) · 2023Review
- Antipsychotic Drug-Mediated Adverse Effects on Rat Testicles May Be Caused by Altered Redox and Hormonal Homeostasis.International journal of molecular sciences · 2022Article
- A community pharmacist's intervention in antipsychotic drug-induced sexual dysfunction in a patient with schizophrenia.Clinical case reports · 2021Article
- Management Strategies for Antipsychotic-Related Sexual Dysfunction: A Clinical Approach.Journal of clinical medicine · 2021Review
- Sexuality in Ultra-High Risk for Psychosis and First-Episode Psychosis. A Systematic Review of Literature.Frontiers in psychiatry · 2021Review
- The Effect of Liver and Kidney Disease on the Pharmacokinetics of Clozapine and Sildenafil: A Physiologically Based Pharmacokinetic Modeling.Drug design, development and therapy · 2020Article
- Adverse drug reactions experienced by out-patients taking chlorpromazine or haloperidol at Zomba Mental Hospital, Malawi.BMC research notes · 2019Observational
- Serotonergic, Dopaminergic, and Noradrenergic Modulation of Erotic Stimulus Processing in the Male Human Brain.Journal of clinical medicine · 2019Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Sexual dysfunction is a common condition in patients taking antipsychotics, and is the most bothersome symptom and adverse drug effect, resulting in a negative effect on treatment compliance. It is known that hyperprolactinemia is a major cause of sexual dysfunction. Based on the blockade of dopamine D2 receptors, haloperidol, risperidone, and amisulpride are classed as prolactin-elevating antipsychotics, while olanzapine, clozapine, quetiapine, ziprasidone, and aripiprazole are classed as prolactin-sparing drugs. Risperidone and the other typical antipsychotics are associated with a high rate of sexual dysfunction as compared to olanzapine, clozapine, quetiapine, and aripiprazole. With regard to treatment in patients suffering from sexual dysfunction, sildenafil was associated with significantly more erections sufficient for penetration as compared to a placebo. Subsequent studies are needed in order to provide physicians with a better understanding of this problem, thereby leading toward efficacious and safe solutions.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.