SynthesisDeutsches Arzteblatt international2013
The prevention, diagnosis and treatment of premature labor.
Synthesis in Deutsches Arzteblatt international, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
31 citing papers in PubMed, 91 citations in OpenAlex.
- Association between CACNA1C gene polymorphisms and ritodrine-induced adverse events in preterm labor patients.European journal of clinical pharmacology · 2017Trial
- The Survival of Extremely Premature Neonates in Perinatal Care Centers of Different Care Levels: An Analysis from the German Federal States of Thuringia and Saxony.Deutsches Arzteblatt international · 2025Article
- Reducing the Rate of Premature Births through Early Diagnosis and Pregnancy-Adapted Treatment of Hypothyroidism.Geburtshilfe und Frauenheilkunde · 2023Article
- Prediction of Preterm Labor from the Electrohysterogram Signals Based on Different Gestational Weeks.Sensors (Basel, Switzerland) · 2023Article
- Inadequate Timing Limits the Benefit of Antenatal Corticosteroids on Neonatal Outcome: Retrospective Analysis of a High-Risk Cohort of Preterm Infants in a Tertiary Center in Germany.Geburtshilfe und Frauenheilkunde · 2022Article
- Prediction of Preterm Delivery from Unbalanced EHG Database.Sensors (Basel, Switzerland) · 2022Article
- Healthy preconception and early-pregnancy lifestyle and risk of preterm birth: a prospective cohort study.The American journal of clinical nutrition · 2021Article
- Short-Term Outcomes of Atosiban in the Treatment of Preterm Labour at the Sultan Qaboos University Hospital, Muscat, Oman: A tertiary care experience.Sultan Qaboos University medical journal · 2021Article
- Self-Reported Psychosocial Stress in Parents With Small Children.Deutsches Arzteblatt international · 2020Article
- Craniofacial growth in infants with deformational plagiocephaly: does prematurity affect the duration of head orthosis therapy and the extent of the reduction in asymmetry during treatment?Clinical oral investigations · 2020Article
- [Update on Recommendations for SARS-CoV-2/COVID-19 During Pregnancy, Birth and Childbed].Zeitschrift fur Geburtshilfe und Neonatologie · 2020Article
- Surgery during pregnancy - results of a German questionnaire.Innovative surgical sciences · 2020Article
- Bryophyllum pinnatum enhances the inhibitory effect of atosiban and nifedipine on human myometrial contractility: an in vitro study.BMC complementary and alternative medicine · 2019Article
- Non-Invasive Ventilation in Neonatology.Deutsches Arzteblatt international · 2019Review
- Controversies about the Secondary Prevention of Spontaneous Preterm Birth.Geburtshilfe und Frauenheilkunde · 2018Article
- Granulocytic myeloid-derived suppressor cells (GR-MDSC) accumulate in cord blood of preterm infants and remain elevated during the neonatal period.Clinical and experimental immunology · 2018Article
- Pregnancy in a woman with untreated bladder exstrophy: a case report.Case reports in women's health · 2018Article
- Effects of Late Gestational Fetal Exposure to Dexamethasone Administration on the Postnatal Hypothalamus-Pituitary-Adrenal Axis Response to Hypoglycemia in Pigs.International journal of molecular sciences · 2017Article
- Hypothalamic Amenorrhea and the Long-Term Health Consequences.Seminars in reproductive medicine · 2017Review
- The relationship between macro- and micro-nutrients intake and risk of preterm premature rupture of membranes in pregnant women of Isfahan.Advanced biomedical research · 2016Article
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Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe percentage of preterm births in Germany is high at 9%, but stable. 77% of cases of perinatal death are in prematurely born infants. Intensive research efforts are being directed toward the development of new means of primary and secondary prevention, diagnostic assessment, and pharmacotherapy of premature labor.
methodsWe review pertinent publications that were retrieved by a selective search of the literature from 1966 to 2012, including current meta-analyses from the Cochrane database and the guidelines of German and foreign obstetric societies.
resultsPreterm labor is a multifactorial problem. The current treatment options are symptomatic, rather than causally directed. Preventive treatment with progesterone can lower the rate of preterm birth in high-risk groups by more than 30%. Transporting the pregnant women to an appropriately qualified perinatal care center and induction of fetal lung maturation lowers perinatal mortality. A variety of tocolytic drugs with different mechanisms of action (betamimetics, oxytocin antagonists, calcium-channel blockers, NO donors, and inhibitors of prostaglandin synthesis) can be used for individualized tocolytic treatment. Premature rupture of the membranes is an indication for antibiotics.
conclusionThe goal of all attempts to prevent and treat preterm labor is to improve preterm infants' chances of surviving with as few complications as possible. The methods discussed here can be used to prolong pregnancies at risk for preterm labor and so to reduce perinatal morbidity and mortality.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.