Evidence map›Paper›PMID 23596285›Full record

ArticleJournal of virology2013

Identification of a pegivirus (GB virus-like virus) that infects horses.

Amit Kapoor, Peter Simmonds, John M Cullen, Troels K H Scheel, Jan L Medina, Federico Giannitti, Eiko Nishiuchi, Kenny V Brock, Peter D Burbelo, Charles M Rice and 1 more

Open access · bronzeAbstract read
In one paragraph

Article in Journal of virology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers.

0numbers the graph read from it
0cells of the map it votes in
49citing papers in PubMed
5.7field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

49 citing papers in PubMed, 92 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. The Blood Virome: A new frontier in biomedical science.Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie · 2024
    Review
  5. Review
  6. Review
  7. Review
  8. Review
  9. Article
  10. Equine parvovirus hepatitis.Equine veterinary journal · 2021
    Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Review
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 7 institutions in 3 countries.

Amit KapoorCenter for Infection and Immunity, Columbia University, New York, New York, USA. ak3117@columbia.edu
Peter Simmonds
John M Cullen
Troels K H Scheel
Jan L Medina
Federico Giannitti
Eiko Nishiuchi
Kenny V Brock
Peter D Burbelo
Charles M Rice
W Ian Lipkin
Columbia University · USRockefeller University · USAuburn University · USCopenhagen University Hospital · DKNational Institute of Dental and Craniofacial Research · USUniversity of California, Davis · USUniversity of Edinburgh · GB

Funding

Viral Pathogenesis and TherapeuticsU54AI057158 · NIAID · WADSWORTH CENTER · PI LIPKIN, W. IAN · 2003 to 2014
$100.8M
Development of Complement Modulating Therapeutics for AMDR24EY017404 · NEI · UNIVERSITY OF UTAH · PI HAGEMAN, GREGORY S · 2006 to 2010
$14.8M
Structure and function of the HCV RNA replicaseR01CA057973 · NCI · WASHINGTON UNIVERSITY · PI RICE, CHARLES M · 1992 to 2013
$4.7M
Identification and characterization of cellular factors involved in HCV entryR01AI072613 · NIAID · ROCKEFELLER UNIVERSITY · PI RICE, CHARLES M · 2007 to 2016
$4.7M
Viral Arrays for BiodefenseU01AI070411 · NIAID · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI LIPKIN, W. IAN · 2006 to 2010
$4.4M
Risk of Viral Emergence from BatsR01AI079231 · NIAID · ECOHEALTH ALLIANCE, INC. · PI DASZAK, PETER · 2008 to 2012
$2.6M
Simianizing hepatitis C: Defining the species-tropism of a hepatotropic virusR01AI090055 · NIAID · ROCKEFELLER UNIVERSITY · PI RICE, CHARLES M · 2010 to 2014
$2.1M
Molecular Characterization of Novel AstrovirusesR21AI090196 · NIAID · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI KAPOOR, AMIT · 2010 to 2011
$454k
NCI NIH HHS CA057973NCI NIH HHS R01 CA057973NEI NIH HHS EY017404NEI NIH HHS R24 EY017404NIAID NIH HHS AI070411NIAID NIH HHS AI072613NIAID NIH HHS AI079231NIAID NIH HHS AI090055NIAID NIH HHS AI090196NIAID NIH HHS AI57158NIAID NIH HHS R01 AI072613NIAID NIH HHS R01 AI079231NIAID NIH HHS R01 AI090055NIAID NIH HHS R21 AI090196NIAID NIH HHS U01 AI070411NIAID NIH HHS U54 AI057158Wellcome Trust 095831
6 · The paper itself

Abstract

The recent identification of nonprimate hepaciviruses in dogs and then in horses prompted us to look for pegiviruses (GB virus-like viruses) in these species. Although none were detected in canines, we found widespread natural infection of horses by a novel pegivirus. Unique genomic features and phylogenetic analyses confirmed that the tentatively named equine pegivirus (EPgV) represents a novel species within the Pegivirus genus. We also determined that EPgV causes persistent viremia whereas its clinical significance is undetermined.

Indexed as

Amino Acid SequenceAnimalsBase SequenceFlaviviridaeFlaviviridae InfectionsHorse DiseasesHorsesMolecular Sequence DataPhylogenyPrevalenceSequence Analysis, DNASpecies SpecificityUnited StatesViremia

Identifiers

PMID23596285
PMCPMC3676142
OpenAlexW2117561213

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.