ArticleThe Journal of experimental biology2013
Aging and its modulation in a long-lived worker caste of the honey bee.
Article in The Journal of experimental biology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.
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Who cites it
34 citing papers in PubMed.
- Inter-Caste Comparison Reveals a Unique Bioenergetic Signature in Long-Lived Ant Queens.Molecular ecology · 2025Article
- Seasonal and nutritional modulation of honeybee olfactory learning by the short neuropeptide F.Proceedings. Biological sciences · 2025Article
- Interpreting insect behavior through the lens of executive functions.Frontiers in behavioral neuroscience · 2025Article
- Modeling seasonal immune dynamics of honey bee (Apis mellifera L.) response to injection of heat-killed Serratia marcescens.PloS one · 2024Article
- Article
- SDS-PAGE-Based Quantitative Assay of Hemolymph Proteins in Honeybees: Progress and Prospects for Field Application.International journal of molecular sciences · 2023Article
- Honey bee retinue workers respond similarly to queens despite seasonal differences in Queen Mandibular Pheromone (QMP) signaling.PloS one · 2023Article
- Autofluorescent Biomolecules in Diptera: From Structure to Metabolism and Behavior.Molecules (Basel, Switzerland) · 2022Review
- Social microbiota and social gland gene expression of worker honey bees by age and climate.Scientific reports · 2022Article
- Context-dependent influence of threat on honey bee social network dynamics and brain gene expression.The Journal of experimental biology · 2022Article
- The Biology of Aging in Insects: FromAnnual review of entomology · 2022Review
- Screening bioactive food compounds in honey bees suggests curcumin blocks alcohol-induced damage to longevity and DNA methylation.Scientific reports · 2021Article
- Oxidative stress and senescence in social insects: a significant but inconsistent link?Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2021Article
- Social modulation of ageing: mechanisms, ecology, evolution.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2021Review
- The Importance of Time and Place: Nutrient Composition and Utilization of Seasonal Pollens by European Honey Bees (Insects · 2021Article
- Overwintering Honey Bee Colonies: Effect of Worker Age and Climate on the Hindgut Microbiota.Insects · 2021Article
- Structural aspects of the aging invertebrate brain.Cell and tissue research · 2021Review
- Reproductive potential does not cause loss of heat shock response performance in honey bees.Scientific reports · 2020Article
- The sensitivity of a honeybee colony to worker mortality depends on season and resource availability.BMC evolutionary biology · 2020Article
- Gut microbiota structure differs between honeybees in winter and summer.The ISME journal · 2020Article
Corrections and comments
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Authors and funding
3 authors.
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Abstract
Highly social animals provide alternative aging models in which vastly different lifespan patterns are flexible, and linked to social caste. Research in these species aims to reveal how environment, including social cues, can shape the transition between short-lived and extremely long-lived phenotypes with negligible senescence. Among honey bee workers, short to intermediate lifespans are typical for summer castes, while the winter caste can live up to 10 times longer. For summer castes, experimental interventions could predictably accelerate, slow or revert functional senescence. In contrast, little is known about the partic ular conditions under which periods of negligible senescence in winter castes can be disrupted or sustained. We asked how manipulation of social environment in colonies with long-lived winter bees might alter the pace of functional senescence, measured as learning performance, as well as of cellular senescence, measured as lipofuscin accumulation. We show that behavioral senescence becomes rapidly detectable when the winter state is disrupted, and changes in social task behaviors and social environment (brood) are induced. Likewise, we found that cellular senescence was induced by such social intervention. However, cellular senescence showed marked regional differences, suggesting that particular brain regions age slower than others. Finally, by preventing post-winter colonies from brood rearing, behavioral senescence became undetectable, even after transition to the usually short-lived phenotypes had occurred. We envision that social regulation of negligible functional senescence and highly dynamic accumulation of a universal symptom of cellular aging (lipofuscin) offers rewarding perspectives to target proximate mechanisms of slowed aging.
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