Evidence map›Paper›PMID 23596243›Full record

ArticleJournal of clinical microbiology2013

Real-time optical antimicrobial susceptibility testing.

Marlene Fredborg, Klaus R Andersen, Erik Jørgensen, Aida Droce, Tom Olesen, Bent B Jensen, Flemming S Rosenvinge, Teis E Sondergaard

Open access · bronzeAbstract readEvaluation Study
In one paragraph

Article in Journal of clinical microbiology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 52 papers.

0numbers the graph read from it
0cells of the map it votes in
52citing papers in PubMed
3.2field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

52 citing papers in PubMed, 122 citations in OpenAlex.

  1. Article
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  7. Adaptive laboratory evolution ofFrontiers in microbiology · 2023
    Article
  8. Why do lactic acid bacteria thrive in chain elongation microbiomes?Frontiers in bioengineering and biotechnology · 2023
    Article
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  10. Review
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  20. Recent Advances in the Detection of Antibiotic and Multi-Drug ResistantInternational journal of molecular sciences · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Marlene FredborgDepartment of Animal Science, Faculty of Science and Technology, Aarhus University, Tjele, Denmark. marlene.fredborg@agrsci.dk
Klaus R Andersen
Erik Jørgensen
Aida Droce
Tom Olesen
Bent B Jensen
Flemming S Rosenvinge
Teis E Sondergaard
Aarhus University · DKUnisense (Denmark) · DKOdense University Hospital · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Rapid antibiotic susceptibility testing is in high demand in health care fields as antimicrobial-resistant bacterial strains emerge and spread. Here, we describe an optical screening system (oCelloScope) which, based on time-lapse imaging of 96 bacteria-antibiotic combinations at a time, introduces real-time detection of bacterial growth and antimicrobial susceptibility with imaging material to support the automatically generated graphs. Automated antibiotic susceptibility tests of a monoculture showed statistically significant antibiotic effects within 6 min and within 30 min in complex samples from pigs suffering from catheter-associated urinary tract infections. The oCelloScope system provides a fast high-throughput screening method for detecting bacterial susceptibility that might entail an earlier diagnosis and introduction of appropriate targeted therapy and thus combat the threat from multidrug-resistant pathogenic bacteria. The oCelloScope system can be employed for a broad range of applications within bacteriology and might present new vistas as a point-of-care instrument in clinical and veterinary settings.

Indexed as

AnimalsAnti-Bacterial AgentsAutomation, LaboratoryBacteriaCatheter-Related InfectionsDisease Models, AnimalMicrobial Sensitivity TestsOptical ImagingSwineTime FactorsTime-Lapse ImagingUrinary Tract InfectionsAnti-Bacterial Agents

Identifiers

PMID23596243
PMCPMC3697729
OpenAlexW2144209134

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.