Evidence map›Paper›PMID 23596095›Full record

ArticlePharmacoepidemiology and drug safety2013

Methods of linking mothers and infants using health plan data for studies of pregnancy outcomes.

Karin E Johnson, Sarah J Beaton, Susan E Andrade, T Craig Cheetham, Pamela E Scott, Tarek A Hammad, Inna Dashevsky, William O Cooper, Robert L Davis, Pamala A Pawloski and 6 more

Abstract readMulticenter Study
In one paragraph

Article in Pharmacoepidemiology and drug safety, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

  1. Article
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  5. Observational
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  7. Article
  8. The Adolescent and Young Adult (AYA) Horizon Study: An AYA Cancer Survivorship Cohort.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2021
    Article
  9. Article
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  11. Article
  12. Review
  13. Power in numbers.Rheumatology (Oxford, England) · 2018
    Article
  14. Review
  15. Article
  16. Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Karin E JohnsonGroup Health Research Institute, Group Health Cooperative, Seattle, WA, USA.
Sarah J Beaton
Susan E Andrade
T Craig Cheetham
Pamela E Scott
Tarek A Hammad
Inna Dashevsky
William O Cooper
Robert L Davis
Pamala A Pawloski
Marsha A Raebel
David H Smith
Sengwee Toh
De-Kun Li
Katherine Haffenreffer
Sascha Dublin

Funding

Pharmacepidemiology in the elderly: medications pneumonia risk and confoundingK23AG028954 · NIA · KAISER FOUNDATION HEALTH PLAN OF WASHINGTON · PI DUBLIN, SASCHA · 2007 to 2011
$864k
NIA NIH HHS K23 AG028954NIA NIH HHS K23AG028954PHS HHS HHSF223200510008CPHS HHS HHSF223200510009CPHS HHS HHSF223200510012C
6 · The paper itself

Abstract

purposeResearch on medication safety in pregnancy often utilizes health plan and birth certificate records. This study discusses methods used to link mothers with infants, a crucial step in such research.

methodsWe describe how eight sites participating in the Medication Exposure in Pregnancy Risk Evaluation Program created linkages between deliveries, infants and birth certificates for the 2001-2007 birth cohorts. We describe linkage rates across sites, and for two sites, we compare the characteristics of populations linked using different methods.

resultsOf 299,260 deliveries, 256,563 (86%; range by site, 74-99%) could be linked to infants using a deterministic algorithm. At two sites, using birth certificate data to augment mother-infant linkage increased the representation of mothers who were Hispanic or non-White, younger, Medicaid recipients, or had low educational level. A total of 236,460 (92%; range by site, 82-100%) deliveries could be linked to a birth certificate.

conclusionsTailored approaches enabled linking most deliveries to infants and to birth certificates, even when data systems differed. The methods used may affect the composition of the population identified. Linkages established with such methods can support sound pharmacoepidemiology studies of maternal drug exposure outside the context of a formal registry.

Indexed as

Databases, FactualMedical Record LinkageMedical Records Systems, ComputerizedPerinatal CarePregnancy OutcomeAdolescentAdultAdverse Drug Reaction Reporting SystemsAlgorithmsBirth CertificatesChi-Square DistributionData MiningDrug PrescriptionsDrug Utilization ReviewEthnicityFemalebirth certificatesMedicaidmedical record linkagepharmacoepidemiologypregnancy outcome/epidemiology

Identifiers

PMID23596095
PMCPMC3707923

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.