Evidence map›Paper›PMID 23596082›Full record

ArticleObesity (Silver Spring, Md.)2013

Racial/ethnic differences in clinical and biochemical type 2 diabetes mellitus risk factors in children.

Michael Rosenbaum, Ilene Fennoy, Siham Accacha, Lisa Altshuler, Dennis E Carey, Stephen Holleran, Robert Rapaport, Steven P Shelov, Phyllis W Speiser, S Ten and 13 more

Open access · bronzeAbstract read
In one paragraph

Article in Obesity (Silver Spring, Md.), 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
3.9field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 27 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Impacts of a Standing Desk Intervention within an English Primary School Classroom: A Pilot Controlled Trial.International journal of environmental research and public health · 2020
    Article
  6. Article
  7. Review
  8. Ethnic and Sex Differences in Adiponectin: From Childhood to Adulthood.The Journal of clinical endocrinology and metabolism · 2016
    Article
  9. Article
  10. Review
  11. Adolescent Obesity and Its Risks: How to Screen and When to Refer.Journal of clinical outcomes management : JCOM · 2014
    Article
  12. Article
  13. Article
  14. Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

23 authors at 8 institutions in 1 country.

Michael RosenbaumPediatrics Department, New York Presbyterian Hospital/Columbia University Medical Center, New York, New York, USA.
Ilene Fennoy
Siham Accacha
Lisa Altshuler
Dennis E Carey
Stephen Holleran
Robert Rapaport
Steven P Shelov
Phyllis W Speiser
S Ten
Amrit Bhangoo
Claudia Boucher-Berry
Yomery Espinal
Rishi Gupta
Abeer A Hassoun
Loretta Iazetti
Fabienne Jean-Jacques
Amy M Jean
Michelle L Klein
Robet Levine
Barbara Lowell
Lesley Michel
Warren Rosenfeld
Winthrop-University Hospital · USCohen Children's Medical Center · USBoston Children's Hospital · USNew York Hospital Queens · USNewYork–Presbyterian Hospital · USMaimonides Medical Center · USMount Sinai Hospital · USColumbia University Irving Medical Center · US

Funding

Translational Biomarker Analytical Core (TBAC)P30DK063608 · NIDDK · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI DOMENICO ACCILI · 2003 to 2026
$36.7M
Clinical and Translational Science AwardUL1TR000040 · NCATS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI GINSBERG, HENRY N · 2012 to 2015
$26.2M
Training Grant in Pediatric Endocrinology, Diabetes and MetabolismT32DK065522 · NIDDK · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI SHARON E. OBERFIELD · 2005 to 2026
$4.6M
NCATS NIH HHS UL1 TR000040NCATS NIH HHS UL1TR000040NIDDK NIH HHS 5T 32DK 06552-07NIDDK NIH HHS P30 DK063608NIDDK NIH HHS P30 DK63068NIDDK NIH HHS T32 DK065522
6 · The paper itself

Abstract

objectiveTo examine whether periadolescent children demonstrate the significant racial/ethnic differences in body fatness relative to BMI and in the prevalence and relationship of body composition to risk factors for type 2 diabetes (T2DM) as in adults. DESIGN AND

methodsFamily history of obesity and T2DM, anthropometry, insulin sensitivity and secretory capacity, lipids, and cytokines (IL-6, CRP, TNF-α, and adiponectin) were examined in a cohort of 994 middle school students (47% male, 53%, female; 12% African American, 14% East Asian, 13% South Asian, 9% Caucasian, 44% Hispanic, and 8% other).

resultsFractional body fat content was significantly greater at any BMI among South Asians. There were racial/ethnic specific differences in lipid profiles, insulin secretory capacity, insulin sensitivity, and inflammatory markers corrected for body fatness that are similar to those seen in adults. Family history of T2DM was associated with lower insulin secretory capacity while family history of obesity was more associated with insulin resistance.

conclusionsChildren show some of the same racial/ethnic differences in risk factors for adiposity-related comorbidities as adults. BMI and waist circumference cutoffs to identify children at-risk for adiposity-related comorbidities should be adjusted by racial/ethnic group as well as other variables such as birthweight and family history.

Indexed as

AdiponectinAdipose TissueAdolescentAsian PeopleBlack or African AmericanBody CompositionBody Mass IndexChildC-Reactive ProteinDiabetes Mellitus, Type 2FemaleHispanic or LatinoHumansInsulinInsulin ResistanceInterleukin-6AdiponectinC-Reactive ProteinInsulinInterleukin-6LipidsTumor Necrosis Factor-alpha

Identifiers

PMID23596082
PMCPMC3766484
OpenAlexW1594236129

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.