Evidence map›Paper›PMID 23595806›Full record

ArticleChild's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery2013

Pediatric brain tumors in Nigeria: clinical profile, management strategies, and outcome.

E O Uche, M T Shokunbi, A O Malomo, E E U Akang, I Lagunju, S D Amanor-Boadu

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Article in Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
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  5. Review
  6. Article
  7. Article
  8. Neuroophthalmic Manifestations of Intracranial Tumours in Children.Case reports in ophthalmological medicine · 2021
    Article
  9. Patterns, treatments, and outcomes of pediatric central nervous system tumors in Sudan: a single institution experience.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2019
    Article
  10. Review
  11. Article
  12. Pediatric central nervous system tumors: review of a single Portuguese institution.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2016
    Article
  13. Review
  14. Article
  15. Article
  16. Article
  17. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

E O UcheDepartment of Neurological Surgery, Institute of Neurosciences, University College Hospital, Ibadan, Oyo State, Nigeria. kechyenny@yahoo.com.
M T ShokunbiDepartment of Neurological Surgery, Institute of Neurosciences, University College Hospital, Ibadan, Oyo State, Nigeria.
A O MalomoDepartment of Neurological Surgery, Institute of Neurosciences, University College Hospital, Ibadan, Oyo State, Nigeria.
E E U AkangDepartment of Pathology, University College Hospital, Ibadan, Oyo State, Nigeria.
I LagunjuDepartment of Pediatrics, University College Hospital, Ibadan, Oyo State, Nigeria.
S D Amanor-BoaduDepartment of Anesthesia, University College Hospital, Ibadan, Nigeria.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionAlthough modern neuroimaging has facilitated early care of brain tumors in children worldwide, there are, however, few published reports on clinical profile, treatment, and outcome of brain tumors in children from our subregion. PURPOSE: We aimed to retrospectively study the clinical profile and outcome of pediatric brain tumors in a tertiary referral center from a developing country.

methodsForty pediatric patients with histologically verified brain tumors managed by the authors over a 13-year period (May 1994-April 2006) were studied. Patients' data from clinical, radiological, and pathology records were analyzed using the statistical package for social sciences version 16.

resultsThe mean age was 9.75 years (range 1-15 years). Twenty-two males, 18 females. Common presenting symptoms were headaches (23 patients, 57.5%) and seizures (15 patients, 37.5%). Hyperreflexia (72.5%) and focal motor deficits (62.5%) were the most common neurologic signs. The mean interval from onset of symptoms to neurosurgical diagnosis was 13.4 months (95% CI). All patients had tumor resection, while 11 (27.5%) patients received adjuvant radiotherapy. Hydrocephalus occurred in 19 (47.5%) patients and was associated with early presentation (X2 = 10.65, p < 0.01). Low-grade astrocytoma (25%) and medulloblastoma (25%) were the most common tumors. Survival at 1 and 5 years were 56 and 47%, respectively.

conclusionFocal motor signs and elevated intracranial pressure are the salient presenting features of brain tumors in children seen in Nigeria. Those of them with hydrocephalus are likely to present early. The outcome for pediatric brain tumors remains poor.

Indexed as

Neurosurgical ProceduresRadiotherapy, AdjuvantAdolescentAstrocytomaBrain NeoplasmsCerebellar NeoplasmsChildChild, PreschoolDeveloping CountriesFemaleHeadacheHumansHydrocephalusInfantMaleMedulloblastomaBrain tumorClinical profileHistologyNeuroimagingOutcomePediatric

Identifiers

PMID23595806

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.