ReviewEuropean journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology2013
Disseminated toxoplasmosis in non-allografted patients with hematologic malignancies: report of two cases and literature review.
Review in European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed, 31 citations in OpenAlex.
- Spinal Cord Toxoplasmosis: Mapping the Journey of a Rare Entity Through a Case Report and Review of the Literature.Microorganisms · 2026Article
- Serological and molecular detection of Toxoplasma Gondii among cancer patients in Sohag, Upper Egypt: a case-control study.Scientific reports · 2025Article
- Cerebral Infectious Opportunistic Lesions in a Patient with Acute Myeloid Leukaemia: The Challenge of Diagnosis and Clinical Management.Antibiotics (Basel, Switzerland) · 2024Article
- Serological and molecular detection ofJournal of parasitic diseases : official organ of the Indian Society for Parasitology · 2023Article
- Longitudinally extensive spinal cord lesion: keep toxoplasmosis in mind.Acta neurologica Belgica · 2023Article
- Seroprevalence ofPeerJ · 2022Article
- Neurotoxoplasmosis in a Patient with Chronic Lymphocytic Leukemia.Journal of the Belgian Society of Radiology · 2021Article
- Toxoplasmosis in a patient receiving ixekizumab for psoriasis.JAAD case reports · 2020Article
- Increased Risk ofBioMed research international · 2020Article
- Article
- High frequency of infection of lung cancer patients with the parasiteERJ open research · 2019Article
- A case of pulmonary toxoplasmosis resembling multiple lung metastases of nasal lymphoma in a cat receiving chemotherapy.The Journal of veterinary medical science · 2018Article
- Treatment of Toxoplasmosis: Historical Perspective, Animal Models, and Current Clinical Practice.Clinical microbiology reviews · 2018Review
- Seroprevalence and Molecular Evaluation of Toxoplasmosis in Patients Undergoing Chemotherapy for Malignancies in the Bushehr Province, Southwest Iran.Jundishapur journal of microbiology · 2016Article
- Toxoplasma Encephalitis in Atypical Hosts at an Academic Cancer Center.Open forum infectious diseases · 2016Article
- Toxoplasmosis complicating lung cancer: a case report.International medical case reports journal · 2015Article
- Toxoplasmic Encephalitis with Untreated Hairy Cell Leukemia Variant.Internal medicine (Tokyo, Japan)Article
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Authors and funding
10 authors at 5 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Toxoplasmosis can be a severe opportunistic infection in patients with acquired immunodeficiency syndrome (AIDS), and also among solid organ transplant and allogeneic hematopoietic stem cell transplant (HSCT) patients. Patients with low-grade or chronic hematologic malignancies are treated with increasing immunosuppressive regimens and, therefore, represent an emerging population at risk for opportunistic diseases. We report here two cases of disseminated toxoplasmosis occurring in non-allografted hematologic patients with chronic lymphoproliferations. A review of 44 cases from the literature reveals that toxoplasmosis occurs increasingly in indolent B cell lymphoproliferative disorders. Aggressive lymphoproliferations, adenosine analogs, autologous HSCT, and the absence of chemoprophylaxis are the main risk factors for opportunistic toxoplasmosis. The central nervous system is the main organ involved. Fever is only present in half of all cases. Latent Toxoplasma cysts reactivation (LTCR) is the most common, but primary infection occurs in about 20% of cases. Global mortality is over 50%.
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