ArticleIntensive care medicine2013
Correlation of thermodilution-derived extravascular lung water and ventilation/perfusion-compartments in a porcine model.
Article in Intensive care medicine, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed.
- Treatment with senicapoc in a porcine model of acute respiratory distress syndrome.Intensive care medicine experimental · 2021Article
- Endexpiratory lung volume measurement correlates with the ventilation/perfusion mismatch in lung injured pigs.Respiratory research · 2017Article
- Inhalation therapy with the synthetic TIP-like peptide AP318 attenuates pulmonary inflammation in a porcine sepsis model.BMC pulmonary medicine · 2015Article
- Low tidal volume pressure support versus controlled ventilation in early experimental sepsis in pigs.Respiratory research · 2014Article
- TIP peptide inhalation in experimental acute lung injury: effect of repetitive dosage and different synthetic variants.BMC anesthesiology · 2014Article
- TIP peptide inhalation in oleic acid-induced experimental lung injury: a post-hoc comparison.BMC research notes · 2013Article
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThis study examines the correlation between the transpulmonary thermodilution derived extravascular lung water content (EVLW) and the ventilation/perfusion-distribution ([Formula: see text]) measured by multiple inert gas elimination (MIGET) in a porcine model.
methods[Formula: see text] measured by micropore membrane inlet mass spectrometry-MIGET (MMIMS-MIGET) and EVLW were simultaneously measured in twelve pigs in the heathy state, with impaired gas exchange from repetitive lung lavage and after 3 h of ventilation. The relationship between [Formula: see text] compartments and EVLW was analysed by linear correlation and regression.
resultsConsiderable increases in EVLW and [Formula: see text] mismatching were induced through the lavage procedure. Significant correlations between the EVLW and the [Formula: see text] fractions representing pulmonary shunt and low [Formula: see text] were found. Perfusion to the normal [Formula: see text] regions was inversely correlated to the EVLW.
conclusionsIncreased EVLW is associated with increased low [Formula: see text] and shunt, but not equal to pulmonary shunt alone. Beneath true shunt EVLW can also be associated with low [Formula: see text] regions.
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