Evidence map›Paper›PMID 23595343›Full record

ArticlePlant foods for human nutrition (Dordrecht, Netherlands)2013

Cooked common beans (Phaseolus vulgaris) protect against β-cell damage in streptozotocin-induced diabetic rats.

Diego Hernández-Saavedra, Magdalena Mendoza-Sánchez, Hebert L Hernández-Montiel, Horacio S Guzmán-Maldonado, Guadalupe F Loarca-Piña, Luis M Salgado, Rosalía Reynoso-Camacho

Abstract read
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In one paragraph

Article in Plant foods for human nutrition (Dordrecht, Netherlands), 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.8field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 30 citations in OpenAlex.

  1. Trial
  2. Article
  3. Novel Insights intoMolecules (Basel, Switzerland) · 2024
    Article
  4. Article
  5. Daily Intake of aFrontiers in nutrition · 2022
    Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Diego Hernández-SaavedraResearch and Graduate Studies in Food Science, School of Chemistry, UAQ, Santiago de Querétaro, Querétaro, México.
Magdalena Mendoza-Sánchez
Hebert L Hernández-Montiel
Horacio S Guzmán-Maldonado
Guadalupe F Loarca-Piña
Luis M Salgado
Rosalía Reynoso-Camacho
Autonomous University of Queretaro · MXInstituto Politécnico Nacional · MXUniversity of Celaya · MX

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Diabetes is a disease characterized by a hyperglycemic stage that leads to a chronic inflammatory state. We evaluated the in vivo effect of a diet supplemented with 25 % cooked black bean cultivar Negro 8025 (N8025) flour in streptozotocin-induced diabetic rats. The effect was assessed before (preventive-treatment) and after (treatment) the onset of diabetes. There is a significant decrease of total phenolic, tannins and anthocyanins content after cooking, and the concentration of most of the single phenols analyzed are only slightly decreased. The treatment group showed a significant reduction of glucose (22.8 %), triglycerides (21.9 %), total cholesterol (29.9 %) and LDL (56.1 %) that correlates with a protection of pancreatic ß-cells. The diet with N8025 flour before the induction of diabetes did not exert a protective effect (glucose levels are similar to the diabetic control) but they have low levels of total cholesterol (47.5 %) and LDL (56.1 %). The preventive-treatment group did not inhibit the increase of TNF-α and IL-1β, whereas the treatment group did, compared to the diabetic control. Therefore, N8025 bean supplementation can be recommended to control diabetes.

Indexed as

PhaseolusAnimalsAnthocyaninsCholesterolCookingDiabetes Mellitus, ExperimentalGlucoseHypoglycemic AgentsInsulin-Secreting CellsLipid MetabolismMalePancreasPhenolsRats, WistarStreptozocinTanninsAnthocyaninsCholesterolGlucoseHypoglycemic AgentsPhenolsStreptozocinTanninsTriglyceridesTumor Necrosis Factor-alpha

Identifiers

PMID23595343
OpenAlexW2169905064

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.