Evidence map›Paper›PMID 23594223›Full record

ArticleActa orthopaedica2013

Impaction grafting of the acetabulum with ceramic bone graft substitute mixed with femoral head allograft: high survivorship in 43 patients with a median follow-up of 7 years: a follow-up report.

Michael R Whitehouse, Peter J Dacombe, Jason C J Webb, Ashley W Blom

Open access · goldAbstract read
In one paragraph

Article in Acta orthopaedica, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it, 24 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Michael R WhitehouseMusculoskeletal Research Unit, Department of Academic Orthopaedics, University of Bristol, Lower Level AOC, Southmead Hospital, Westbury-on-Trym, UK. michael.whitehouse@bristol.ac.uk
Peter J Dacombe
Jason C J Webb
Ashley W Blom
Southmead Hospital · GBUniversity of Bristol · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background and purposeRestoration of bone stock at revision hip surgery remains a challenge. Alternative graft materials with suitable mechanical properties for impaction grafting have been sought due to issues with infection, antigenicity, cost, and availability of allograft. We have previously presented good short-term results of the use of BoneSave, a biphasic porous ceramic bone graft substitute, consisting of sintered 80% tricalcium phosphate and 20% hydroxyapatite, in a 50:50 mix with femoral head allograft. We now present the medium-term results.

methodsWe conducted a retrospective review of a cohort of 43 consecutive patients undergoing impaction grafting of contained acetabular defects by multiple surgeons at a single center. 34 patients received uncemented acetabular components and 9 received cemented components. Patients were followed up radiographically and with the self-reported satisfaction scale (SAPS), Oxford hip score (OHS), and the Short-Form 12 (SF12) health survey. Kaplan-Meier survivorship analysis was performed with revision of the acetabular component, revision of any part of the construct, and reoperation as endpoints.

resultsThe fate of all cases was known. Median follow-up of the surviving patients was 80 (69-106) months. 15 patients died during the follow-up period, 14 with their construct in situ. The survivorship of the grafted acetabulum and acetabular component was 94% (95% CI: 99-78) at 7 years. 1 patient had been revised for aseptic loosening of the acetabulum and 1 for deep infection. The mean OHS was 31 (SD 12), the mean SF12 physical-component score (PCS) was 38 (SD 13), the median SAPS was 83 (0-100), and the median SF12 mental-component score (MCS) was 55 (23-65). The graft material became incorporated in all 3 zones of the acetabulum in 23 out of 24 cases that had complete radiographic follow-up.

interpretationThese medium-term results show that BoneSave is a reliable material for impaction grafting of the acetabulum when used in conjunction with femoral head allograft.

Indexed as

CeramicsProsthesis FailureAcetabulumAdultAgedAged, 80 and overArthroplasty, Replacement, HipBone TransplantationFemaleFemur HeadFollow-Up StudiesHumansKaplan-Meier EstimateMaleMiddle AgedProsthesis Design

Identifiers

PMID23594223
PMCPMC3768035
OpenAlexW2041144126

What OpenQuestion holds

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LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.