ReviewCritical reviews in biochemistry and molecular biology
Metabolism as an integral cog in the mammalian circadian clockwork.
Review in Critical reviews in biochemistry and molecular biology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
13 citing papers in PubMed, 18 citations in OpenAlex.
- Circadian timing of the dystrophin associated complex across the brain and body.Fluids and barriers of the CNS · 2026Review
- Meal timing and its role in obesity and associated diseases.Frontiers in endocrinology · 2024Review
- Timing of Food Intake: Identifying Contributing Factors to Design Effective Interventions.Advances in nutrition (Bethesda, Md.) · 2019Review
- The erythrocyte membrane stability is associated with sleep time and social jetlag in shift workers.PloS one · 2019Article
- The impact of meal timing on cardiometabolic syndrome indicators in shift workers.Chronobiology international · 2017Article
- Molecular Mechanisms of Bipolar Disorder: Progress Made and Future Challenges.Frontiers in cellular neuroscience · 2017Review
- Physiological processes underlying organ injury in alcohol abuse.American journal of physiology. Endocrinology and metabolism · 2016Review
- Biotinylation: a novel posttranslational modification linking cell autonomous circadian clocks with metabolism.American journal of physiology. Heart and circulatory physiology · 2016Article
- Assessing Cardiac Metabolism: A Scientific Statement From the American Heart Association.Circulation research · 2016Review
- Plastic oscillators and fixed rhythms: changes in the phase of clock-gene rhythms in the PVN are not reflected in the phase of the melatonin rhythm of grass rats.Neuroscience · 2015Article
- REV-ERB and ROR nuclear receptors as drug targets.Nature reviews. Drug discovery · 2014Review
- Shift work and circadian dysregulation of reproduction.Frontiers in endocrinology · 2013Article
- Chemotherapeutic Effect of SR9009, a REV-ERB Agonist, on the Human Glioblastoma T98G Cells.ASN neuroArticle
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
Circadian rhythms are an integral part of life. These rhythms are apparent in virtually all biological processes studies to date, ranging from the individual cell (e.g. DNA synthesis) to the whole organism (e.g. behaviors such as physical activity). Oscillations in metabolism have been characterized extensively in various organisms, including mammals. These metabolic rhythms often parallel behaviors such as sleep/wake and fasting/feeding cycles that occur on a daily basis. What has become increasingly clear over the past several decades is that many metabolic oscillations are driven by cell-autonomous circadian clocks, which orchestrate metabolic processes in a temporally appropriate manner. During the process of identifying the mechanisms by which clocks influence metabolism, molecular-based studies have revealed that metabolism should be considered an integral circadian clock component. The implications of such an interrelationship include the establishment of a vicious cycle during cardiometabolic disease states, wherein metabolism-induced perturbations in the circadian clock exacerbate metabolic dysfunction. The purpose of this review is therefore to highlight recent insights gained regarding links between cell-autonomous circadian clocks and metabolism and the implications of clock dysfunction in the pathogenesis of cardiometabolic diseases.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.