ArticleAmerican journal of cancer research2013
Increasing frequency of reirradiation studies in radiation oncology: systematic review of highly cited articles.
Article in American journal of cancer research, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Prospective randomized clinical studies involving reirradiation: update of a systematic review.Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] · 2023Pooled it
- Prospective randomized clinical studies involving reirradiation : Lessons learned.Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] · 2016Pooled it
- Stereotactic radiosurgery (SRS) for brain metastases: a systematic review.Radiation oncology (London, England) · 2014Pooled it
- A prospective audit of thoracic reirradiation practice and peer-review in a high-volume academic center.Technical innovations & patient support in radiation oncology · 2025Article
- Efficacy and safety of twice-daily accelerated hyperfractionated re-irradiation for thoracic malignancies.Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology · 2025Article
- Reirradiation practices of Radiation Therapists (RePoRT) study.Technical innovations & patient support in radiation oncology · 2025Article
- Review and recommendations on deformable image registration uncertainties for radiotherapy applications.Physics in medicine and biology · 2023Review
- Article
- Efficacy and safety analysis in metastatic cancer patients treated with multiple courses of repeat radiation therapy.Clinical and translational radiation oncology · 2023Article
- Cyberknife Radiosurgery for Prostate Cancer after Abdominoperineal Resection (CYRANO): The Combined Computer Tomography and Electromagnetic Navigation Guided Transperineal Fiducial Markers Implantation Technique.Current oncology (Toronto, Ont.) · 2023Article
- The value of moderate dose escalation for re-irradiation of recurrent or second primary head-and-neck cancer.Radiation oncology (London, England) · 2020Article
- A prospective phase II trial on reirradiation of brain metastases with radiosurgery.Clinical and translational radiation oncology · 2019Article
- Reirradiation of Recurrent Pediatric Brain Tumors after Initial Proton Therapy.International journal of particle therapy · 2016Article
- Optimization of re-irradiation using deformable registration: a case study.BJR case reports · 2016Article
- Reirradiation of recurrent medulloblastoma: does clinical benefit outweigh risk for toxicity?Cancer · 2014Article
- When is re-irradiation in head and neck squamous cell carcinoma not indicated?European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2014Article
- Development of a score predicting survival after palliative reirradiation.Journal of oncology · 2014Article
- Preserving the legacy of reirradiation: A narrative review of historical publications.Advances in radiation oncologyReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesIdentification of the most influential scientific publications and directions of mainstream reirradiation research.
methodsA systematic search of the database Scopus (Elsevier B.V., www.scopus.com) was performed, which focused on the time period 1998-2010. Patterns of citation were analysed (total number of citations accumulated independently of their origin and proportion of highly cited articles, arbitrarily defined as those with ≥50 citations).
resultsUp to 64 articles were published each year. Numbers increased over time, especially after the year 2007. Among all 76 articles with at least 50 citations, 28 (37%) focused on head and neck cancer, 27 (36%) on brain tumours including metastases, and 5 (7%) on bone metastases. Most articles evaluated external beam approaches while 10 (13%) focused on brachytherapy. Many of the often quoted publications reported on stereotactic and/or intensity-modulated radiotherapy. Two (3%) reported on randomised clinical studies and 10 (13%) on non-randomised prospective clinical studies (single institution or cooperative group). Only two articles (3%) reported on experimental animal studies.
conclusionsThe number of published reirradiation studies has increased in recent years. Many studies examined highly conformal and precise radiotherapy, in particular of brain and head and neck tumours. Given that few randomised clinical trials were published, efforts to increase this type of research activity are warranted.
Indexed as
Identifiers
23593538PMC3623835What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.