Evidence map›Paper›PMID 23592698›Full record

ArticleAdvanced healthcare materials2013

Triggered drug release from superhydrophobic meshes using high-intensity focused ultrasound.

Stefan T Yohe, Jonathan A Kopechek, Tyrone M Porter, Yolonda L Colson, Mark W Grinstaff

Abstract read
In one paragraph

Article in Advanced healthcare materials, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Stefan T YoheDepartments of Biomedical Engineering and Chemistry, Boston University, Boston, MA 02215.
Jonathan A Kopechek
Tyrone M Porter
Yolonda L Colson
Mark W Grinstaff

Funding

Boston University Cross-Disciplinary Training in Nanotechnology for CancerR25CA153955 · NCI · BOSTON UNIVERSITY (CHARLES RIVER CAMPUS) · PI FALLER, DOUGLAS V, GOLDBERG, BENNETT B · 2010 to 2014
$2.1M
Flexible, Conformal, Polymeric Films for Lung Resection MarginsR01CA149561 · NCI · BOSTON UNIVERSITY (CHARLES RIVER CAMPUS) · PI COLSON, YOLONDA L, GRINSTAFF, MARK W. · 2011 to 2014
$1.4M
NCI NIH HHS R01 CA149561NCI NIH HHS R01CA149561NCI NIH HHS R25 CA153955
6 · The paper itself

Abstract

Application of high-intensity focused ultrasound to drug-loaded superhydrophobic meshes affords triggered drug release by displacing an entrapped air layer. The air layer within the superhydrophobic meshes is characterized using direct visualization and B-mode imaging. Drug-loaded superhydrophobic meshes are cytotoxic in an in vitro assay after ultrasound treatment.

Indexed as

UltrasonicsAntineoplastic Agents, PhytogenicCamptothecinCell SurvivalDrug CarriersHumansHydrophobic and Hydrophilic InteractionsIrinotecanMCF-7 CellsPolyestersAntineoplastic Agents, PhytogenicCamptothecinDrug CarriersIrinotecanpolycaprolactonePolyesterspoly(glycerol monosterate-co-epsilon-caprolactone)biomaterialsdrug deliveryelectrospinningHIFUmeshessuperhydrophobictriggeredultrasound

Identifiers

PMID23592698
PMCPMC3923359

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.