Evidence map›Paper›PMID 23592572›Full record

ArticleAngewandte Chemie (International ed. in English)2013

Dual responsive, stabilized nanoparticles for efficient in vivo plasmid delivery.

Hua Wei, Lisa R Volpatti, Drew L Sellers, Don O Maris, Ian W Andrews, Ashton S Hemphill, Leslie W Chan, David S H Chu, Philip J Horner, Suzie H Pun

Abstract read
In one paragraph

Article in Angewandte Chemie (International ed. in English), 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Intrathecal drug delivery in the era of nanomedicine.Advanced drug delivery reviews · 2020
    Pooled it
  2. Article
  3. Article
  4. Inhibition of SARS-CoV-2 replication in the lung with siRNA/VIPER polyplexes.Journal of controlled release : official journal of the Controlled Release Society · 2022
    Article
  5. Drug delivery to the central nervous system.Nature reviews. Materials · 2022
    Article
  6. Article
  7. Polyplex transfection from intracerebroventricular delivery is not significantly affected by traumatic brain injury.Journal of controlled release : official journal of the Controlled Release Society · 2020
    Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Polyplex Evolution: Understanding Biology, Optimizing Performance.Molecular therapy : the journal of the American Society of Gene Therapy · 2017
    Review
  13. Article
  14. Virus-Inspired Polymer for Efficient In Vitro and In Vivo Gene Delivery.Angewandte Chemie (International ed. in English) · 2016
    Article
  15. Article
  16. Microbubbles and ultrasound increase intraventricular polyplex gene transfer to the brain.Journal of controlled release : official journal of the Controlled Release Society · 2016
    Article
  17. Nano-Sized Sunflower Polycations As Effective Gene Transfer Vehicles.Small (Weinheim an der Bergstrasse, Germany) · 2016
    Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Hua WeiDepartment of Bioengineering and Molecular Engineering and Sciences Institute, University of Washington, Seattle, WA 98195, USA.
Lisa R Volpatti
Drew L Sellers
Don O Maris
Ian W Andrews
Ashton S Hemphill
Leslie W Chan
David S H Chu
Philip J Horner
Suzie H Pun

Funding

Ultrasound-aided gene transfer to direct cortical neurogenesis after brain injuryR01NS064404 · NINDS · UNIVERSITY OF WASHINGTON · PI HORNER, PHILIP J, PUN, SUZIE H. · 2009 to 2018
$3.5M
NINDS NIH HHS 1R01NS064404NINDS NIH HHS R01 NS064404
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Gene Transfer TechniquesDrug CarriersDrug StabilityEndocytosisEndosomesHeLa CellsHumansHydrophobic and Hydrophilic InteractionsMicroscopy, Electron, TransmissionNanoparticlesPlasmidsPolymersRNA, Small InterferingSurface PropertiesTransfectionDrug CarriersPolymersRNA, Small Interfering

Identifiers

PMID23592572
PMCPMC3738056

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.