ArticleAmerican journal of perinatology2014
Accurate automated apnea analysis in preterm infants.
Article in American journal of perinatology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.
What it found
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Who cites it
37 citing papers in PubMed, 60 citations in OpenAlex.
- Definitions and monitoring methods for apnea in preterm infants: a scoping review.Pediatric research · 2026Article
- Physiological responses to retinopathy of prematurity screening: indirect ophthalmoscopy versus ultra-widefield retinal imaging.Pediatric research · 2025Article
- Simulated kangaroo care in very preterm infants does not reduce physiological instability: the COSYBABY randomised controlled cross-over trial.Frontiers in pediatrics · 2025Article
- Pharmacological treatment for apnoea of prematurity-the need for an individualised approach.Frontiers in pediatrics · 2025Review
- Neonatal apnea and hypopnea prediction in infants with Robin sequence with neural additive models for time series.PLOS digital health · 2024Article
- Exploring Computational Techniques in Preprocessing Neonatal Physiological Signals for Detecting Adverse Outcomes: Scoping Review.Interactive journal of medical research · 2024Article
- Maturation of cardioventilatory physiological trajectories in extremely preterm infants.Pediatric research · 2024Article
- Article
- Artificial and human intelligence for early identification of neonatal sepsis.Pediatric research · 2023Review
- Article
- Diagnosis and management of cardiopulmonary events in very low birth weight infants close to discharge: a quality improvement initiative.Journal of perinatology : official journal of the California Perinatal Association · 2022Article
- The effect of sensory stimulation on apnea of prematurity.Journal of Taibah University Medical Sciences · 2022Article
- Vital signs as physiomarkers of neonatal sepsis.Pediatric research · 2022Review
- Toward personalized medicine for pharmacological interventions in neonates using vital signs.Paediatric & neonatal pain · 2021Review
- New method to measure interbreath intervals in infants for the assessment of apnoea and respiration.BMJ open respiratory research · 2021Article
- Predicting apneic events in preterm infants using cardio-respiratory and movement features.Computer methods and programs in biomedicine · 2021Article
- Early bradycardia detection and therapeutic interventions in preterm infant monitoring.Scientific reports · 2021Observational
- Apnoea of Prematurity and Neurodevelopmental Outcomes: Current Understanding and Future Prospects for Research.Frontiers in pediatrics · 2021Review
- Pre-discharge Cardiorespiratory Monitoring in Preterm Infants. the CORE Study.Frontiers in pediatrics · 2020Article
- Continuous vital sign analysis for predicting and preventing neonatal diseases in the twenty-first century: big data to the forefront.Pediatric research · 2020Review
Corrections and comments
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Authors and funding
12 authors at 4 institutions in 1 country.
Funding
Abstract
objectiveIn 2006 the apnea of prematurity (AOP) consensus group identified inaccurate counting of apnea episodes as a major barrier to progress in AOP research. We compare nursing records of AOP to events detected by a clinically validated computer algorithm that detects apnea from standard bedside monitors. STUDY
designWaveform, vital sign, and alarm data were collected continuously from all very low-birth-weight infants admitted over a 25-month period, analyzed for central apnea, bradycardia, and desaturation (ABD) events, and compared with nursing documentation collected from charts. Our algorithm defined apnea as > 10 seconds if accompanied by bradycardia and desaturation.
resultsOf the 3,019 nurse-recorded events, only 68% had any algorithm-detected ABD event. Of the 5,275 algorithm-detected prolonged apnea events > 30 seconds, only 26% had nurse-recorded documentation within 1 hour. Monitor alarms sounded in only 74% of events of algorithm-detected prolonged apnea events > 10 seconds. There were 8,190,418 monitor alarms of any description throughout the neonatal intensive care unit during the 747 days analyzed, or one alarm every 2 to 3 minutes per nurse.
conclusionAn automated computer algorithm for continuous ABD quantitation is a far more reliable tool than the medical record to address the important research questions identified by the 2006 AOP consensus group.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.