ReviewLab on a chip2013
Toward giga-pixel nanoscopy on a chip: a computational wide-field look at the nano-scale without the use of lenses.
Review in Lab on a chip, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 55 citations in OpenAlex.
- Development of a Point-of-Care Assay for HIV-1 Viral Load Using Higher Refractive Index Antibody-Coated Microbeads.Sensors (Basel, Switzerland) · 2021Article
- Point-of-care mobile digital microscopy and deep learning for the detection of soil-transmitted helminths and Schistosoma haematobium.Global health action · 2017Article
- Cerebrospinal fluid lens-free microscopy: a new tool for the laboratory diagnosis of meningitis.Scientific reports · 2017Article
- Sparsity-based multi-height phase recovery in holographic microscopy.Scientific reports · 2016Article
- Microfluidic-Based Multi-Organ Platforms for Drug Discovery.Micromachines · 2016Review
- Wide-field imaging of birefringent synovial fluid crystals using lens-free polarized microscopy for gout diagnosis.Scientific reports · 2016Article
- Demosaiced pixel super-resolution for multiplexed holographic color imaging.Scientific reports · 2016Article
- Democratization of Nanoscale Imaging and Sensing Tools Using Photonics.Analytical chemistry · 2015Article
- Nano-imaging enabled via self-assembly.Nano today · 2014Article
- Various on-chip sensors with microfluidics for biological applications.Sensors (Basel, Switzerland) · 2014Review
- Mobile phones democratize and cultivate next-generation imaging, diagnostics and measurement tools.Lab on a chip · 2014Article
- Tunable vapor-condensed nanolenses.ACS nano · 2014Article
- Optical systems for point-of-care diagnostic instrumentation: analysis of imaging performance and cost.Annals of biomedical engineering · 2014Article
- 0.5 gigapixel microscopy using a flatbed scanner.Biomedical optics express · 2013Article
- Giga-pixel fluorescent imaging over an ultra-large field-of-view using a flatbed scanner.Lab on a chip · 2013Article
- On-chip imaging of Schistosoma haematobium eggs in urine for diagnosis by computer vision.PLoS neglected tropical diseases · 2013Article
- Field-portable pixel super-resolution colour microscope.PloS one · 2013Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 1 country.
Funding
Abstract
The development of lensfree on-chip microscopy in the past decade has opened up various new possibilities for biomedical imaging across ultra-large fields of view using compact, portable, and cost-effective devices. However, until recently, its ability to resolve fine features and detect ultra-small particles has not rivalled the capabilities of the more expensive and bulky laboratory-grade optical microscopes. In this Frontier Review, we highlight the developments over the last two years that have enabled computational lensfree holographic on-chip microscopy to compete with and, in some cases, surpass conventional bright-field microscopy in its ability to image nano-scale objects across large fields of view, yielding giga-pixel phase and amplitude images. Lensfree microscopy has now achieved a numerical aperture as high as 0.92, with a spatial resolution as small as 225 nm across a large field of view e.g., >20 mm(2). Furthermore, the combination of lensfree microscopy with self-assembled nanolenses, forming nano-catenoid minimal surfaces around individual nanoparticles has boosted the image contrast to levels high enough to permit bright-field imaging of individual particles smaller than 100 nm. These capabilities support a number of new applications, including, for example, the detection and sizing of individual virus particles using field-portable computational on-chip microscopes.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.