ArticleNature communications2013
Nuclear retention of the transcription factor NLP7 orchestrates the early response to nitrate in plants.
Article in Nature communications, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 241 papers, 2 of them syntheses that pooled it.
What it found
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Who cites it
241 citing papers in PubMed, 2 syntheses or guidelines pooled it, 567 citations in OpenAlex.
- Primary nitrate responses mediated by calcium signalling and diverse protein phosphorylation.Journal of experimental botany · 2020Pooled it
- A balancing act: how plants integrate nitrogen and water signals.Journal of experimental botany · 2020Pooled it
- Review
- Breeding for Resilient Cereals: Integrating Molecular Networks and Trait-Based Selection to Improve Nitrogen and Water Use Efficiencies.Plant, cell & environment · 2026Review
- The primary nitrate response TGA1 and TGA4 transcription factors are negative regulators of sulfate uptake and metabolism.Plant physiology · 2026Article
- Nitrogen Status Rewires Transcriptional Regulation of Dhurrin, a Dual-Purpose Defense Metabolite inPlant direct · 2026Article
- Genome-wide analyses of NPF and NRT2 reveal a potential role for a key gene, CqNRT2.2, in the quinoa response to nitrate.BMC plant biology · 2026Article
- Functional characterization of PpGS2 promoter in response to hormonal and environmental signals in Kentucky bluegrass.BMC plant biology · 2026Article
- The NRT1.1-NLP7 Nexus: An Integrative Signaling Nexus from Nitrate Sensing to Systemic Adaptation and Structure-Guided Engineering.Plants (Basel, Switzerland) · 2026Review
- Nitrogen-Controlled Host Gatekeeping: Regulatory Chokepoints Across Four Windows for Diazotroph Access.International journal of molecular sciences · 2026Article
- Identification of theInternational journal of molecular sciences · 2026Article
- Progress and new questions in understanding the mechanisms controlling plant nitrogen responses.Plant biotechnology (Tokyo, Japan) · 2026Article
- B-GATA factors are required for nitrogen-responsive growth in Physcomitrium patens and Arabidopsis thaliana.The New phytologist · 2026Article
- A feedback regulatory loop by MAPK-CCA1 engages auxin signalling to stimulate root foraging for nitrate.Nature plants · 2026Article
- The root nodule symbiosis regulator NIN exhibits broad DNA binding specificity conferred by an NLP-inherited motif.Science advances · 2026Article
- Nitrate-induced NLP1 SUMOylation regulates nitrate signaling and root nodulation.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- Antagonistic regulation of nitrogen and drought signaling mediated by NIN-like protein 7 transcription factor inProceedings of the National Academy of Sciences of the United States of America · 2026Article
- Expression of thePlants (Basel, Switzerland) · 2026Article
- High-throughput screening for biostimulant discovery: opportunities to enhance nitrogen use efficiency.Frontiers in plant science · 2026Review
- Combined transcriptome and metabolome analyses reveal that galactose metabolism is vital for tobacco in response to low-nitrate stress.Journal of genetics · 2026Article
181 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 5 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Nitrate is both an important nutrient and a signalling molecule for plants. Although several components of the nitrate signalling pathway have been identified, their hierarchical organization remains unclear. Here we show that the localization of NLP7, a member of the RWP-RK transcription factor family, is regulated by nitrate via a nuclear retention mechanism. Genome-wide analyses revealed that NLP7 binds and modulates a majority of known nitrate signalling and assimilation genes. Our findings indicate that plants, like fungi and mammals, rely on similar nuclear retention mechanisms to instantaneously respond to the availability of key nutrients.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.