Observational studyObesity surgery2013
Early experience with the Incisionless Operating Platform™ (IOP) for the treatment of obesity : the Primary Obesity Surgery Endolumenal (POSE) procedure.
Observational study in Obesity surgery, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers, 3 of them syntheses that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
46 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Primary obesity surgery endoluminal (POSE) for the treatment of obesity: a systematic review and meta-analysis.Surgical endoscopy · 2022Pooled it
- Endoscopic Gastric Plication for Morbid Obesity: a Systematic Review and Meta-analysis of Published Data over Time.Obesity surgery · 2019Pooled it
- Efficacy of Endoscopic Interventions for the Management of Obesity: a Meta-analysis to Compare Endoscopic Sleeve Gastroplasty, AspireAssist, and Primary Obesity Surgery Endolumenal.Obesity surgery · 2019Pooled it
- MILEPOST Multicenter Randomized Controlled Trial: 12-Month Weight Loss and Satiety Outcomes After poseObesity surgery · 2017Trial
- Progress and Challenges in Joining for Precision Endoscope Fabrication.Sensors (Basel, Switzerland) · 2026Review
- Endobariatric Management of Metabolic Dysfunction-Associated Steatotic Liver Disease: A Narrative Review.Biomedicines · 2026Review
- Strategies to Manage Obesity: Endoscopic Bariatric and Metabolic Therapies.Methodist DeBakey cardiovascular journal · 2025Review
- Update on Endoscopic Treatments for Obesity.Current obesity reports · 2024Review
- Metabolic and Bariatric Endoscopy: A Mini-Review.Life (Basel, Switzerland) · 2023Review
- A Comprehensive Review on Bariatric Endoscopy: Where We Are Now and Where We Are Going.Medicina (Kaunas, Lithuania) · 2023Review
- Advances in endobariatrics: past, present, and future.Gastroenterology report · 2023Review
- Endobariatrics: a Still Underutilized Weight Loss Tool.Current treatment options in gastroenterology · 2023Review
- Primary Bariatric Procedures.Digestive diseases and sciences · 2022Review
- Endoscopic Procedures for Weight Loss.Current obesity reports · 2021Review
- Endobariatrics and Metabolic Endoscopy: Can We Solve the Obesity Epidemic with Our Scope?Current gastroenterology reports · 2020Review
- Endoscopic gastric body plication for the treatment of obesity: technical success and safety of a novel technique (with video).Gastrointestinal endoscopy · 2020Article
- The Role of Minimally Invasive and Endoscopic Technologies in Morbid Obesity Treatment: Review and Critical Appraisal of the Current Clinical Practice.Obesity surgery · 2020Review
- Reinforced POSE: the 18-Plication Solution.Obesity surgery · 2019Article
- Endoscopic Bariatric Therapies: Intragastric Balloons, Tissue Apposition, and Aspiration Therapy.Current treatment options in gastroenterology · 2019Review
- Endoscopic bariatric therapies for treating obesity: a learning curve for gastroenterologists.Translational gastroenterology and hepatology · 2019Review
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundWe report our initial experience and 6-month outcomes in a single center using the per-oral Incisionless Operating Platform™ (IOP) (USGI Medical) to place transmural plications in the gastric fundus and distal body using specialized suture anchors (the Primary Obesity Surgery Endolumenal [POSE] procedure).
methodsA prospective observational study was undertaken with institutional Ethics Board approval in a private hospital in Barcelona, Spain. Indicated patients were WHO obesity class I-II, or III, where patients refused a surgical approach.
resultsBetween February 28, 2011 and March 23, 2012, the POSE procedure was successfully performed in 45 patients: 75.6 % female; mean age 43.4 ± 9.2 SD (range 21.0-64.0). At baseline: mean absolute weight (AW, kg), 100.8 ± 12.9 (75.5-132.5); body mass index (BMI, kg/m(2)), 36.7 ± 3.8 (28.1-46.6). A mean 8.2 suture-anchor plications were placed in the fundus, 3.0 along the distal body wall. Mean operative time, 69.2 ± 26.6 min (32.0-126.0); patients were discharged in <24 h. Six-month mean AW was 87.0 ± 10.3 (68.0-111.5); BMI decreased 5.8 to 31.3 ± 3.3 (25.1-38.6) (p < 0.001); EWL was 49.4 %; TBWL, 15.5 %. No mortality or operative morbidity. Minor postoperative side effects resolved with treatment by discharge. Patients reported less hunger and earlier satiety post procedure. Liquid intake began 12 h post procedure with full solids by 6 weeks.
conclusionsAt 6-month follow-up of a prospective case series, the POSE procedure appeared to provide safe and effective weight loss without the scarring, pain, and recovery issues of open and laparoscopic bariatric surgery. Long-term follow-up and further study are required.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.