ArticleCough (London, England)2013
The oesophagus and cough: laryngo-pharyngeal reflux, microaspiration and vagal reflexes.
Article in Cough (London, England), 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
26 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Different interventions in preventing sufentanil-induced cough: a systematic review and network meta-analysis.Frontiers in pharmacology · 2025Pooled it
- Effect of Preadministration of Nalmefene on Sufentanil-Induced Cough During Induction of General Anesthesia in Patients Undergoing Breast Surgery: A Double-Blind Randomized Controlled Trial.Drug design, development and therapy · 2024Trial
- Gastroesophageal Reflux Burden Before and After Exercise Challenge in Children with Poorly Controlled Asthma: A 48-Hour MII-pH Study.Advances in respiratory medicine · 2026Article
- Article
- Visual Findings and Reported Symptoms Do Not Correlate With Laryngopharyngeal Reflux, Underscoring the Need for Confirmatory Diagnostics.Laryngoscope investigative otolaryngology · 2026Article
- WAO - ARIA consensus on chronic cough: Executive summary.The World Allergy Organization journal · 2025Review
- Coughing our guts up: how do we diagnose reflux cough?ERJ open research · 2024Article
- Narrative review of relationship between chronic cough and laryngopharyngeal reflux.Frontiers in medicine · 2024Review
- Prevalence of Micro-Aspiration of Bile Acids in Patients with Primary Lung Cancer: A Cross-Sectional Study.Ethiopian journal of health sciences · 2022Article
- WAO-ARIA consensus on chronic cough - Part II: Phenotypes and mechanisms of abnormal cough presentation -The World Allergy Organization journal · 2021Review
- Bacterial infection in dogs with aspiration pneumonia at 2 tertiary referral practices.Journal of veterinary internal medicine · 2021Article
- The Cough Reflex: The Janus of Respiratory Medicine.Frontiers in physiology · 2021Review
- Proteomic Characterization of Canine Gastric Fluid by Liquid Chromatography-Mass Spectrometry for Development of Protein Biomarkers in Regurgitation, Vomiting, and Cough.Frontiers in veterinary science · 2021Article
- Current therapies for gastro-oesophageal reflux in the setting of chronic lung disease: state of the art review.ERJ open research · 2020Review
- Detection of silent reflux events by nuclear scintigraphy in healthy dogs.Journal of veterinary internal medicine · 2020Article
- Medical Therapy of Gastroesophageal Reflux Disease Beyond Proton Pump Inhibitors: Where Are We Heading?Visceral medicine · 2018Review
- Profile of sugammadex for reversal of neuromuscular blockade in the elderly: current perspectives.Clinical interventions in aging · 2018Review
- Fundoplication for laryngopharyngeal reflux despite preoperative dysphagia.Annals of the Royal College of Surgeons of England · 2017Article
- The Role of Microaspiration in the Pathogenesis of Gastroesophageal Reflux-related Chronic Cough.Journal of neurogastroenterology and motility · 2017Article
- Quantifying Laryngopharyngeal Reflux in Singers: Perceptual and Objective Findings.BioMed research international · 2017Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
Gastro-oesophageal reflux disease is generally considered to be one of the commonest causes of chronic cough, however randomised controlled trials of proton pump inhibitors have often failed to support this notion. This article reviews the most recent studies investigating the mechanisms thought to link reflux and cough, namely laryngo-pharyngeal reflux, micro-aspiration and neuronal cross-organ sensitisation. How recent evidence might shed light on the failure of acid suppressing therapies and suggest new approaches to treating reflux related cough are also discussed.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.