ArticleZebrafish2013
A sequence-based variation map of zebrafish.
Article in Zebrafish, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
29 citing papers in PubMed.
- Mapping the Progression of Therapy-Induced Senescence to Therapy Tolerance: An Evolutionarily Conserved Mechanism for Optimizing Cancer Treatment with Senotherapeutics.ACS pharmacology & translational science · 2025Article
- Comparative analysis of zebrafish fear responses to eight different fish species using three-dimensional locomotion-tracking assays.Biology open · 2025Article
- SCAR-6 elncRNA locus epigenetically regulates PROZ and modulates coagulation and vascular function.EMBO reports · 2024Article
- Immune gene variation associated with chromosome-scale differences among individual zebrafish genomes.Scientific reports · 2023Article
- Development and characterization of a new DRCF cell line from Indian wild strain zebrafish Danio rerio (Hamilton 1822).Fish physiology and biochemistry · 2020Article
- Linking Virus Discovery to Immune Responses Visualized during Zebrafish Infections.Current biology : CB · 2020Article
- The Laboratory Domestication of Zebrafish: From Diverse Populations to Inbred Substrains.Molecular biology and evolution · 2020Article
- Genome and Transcriptome Sequencing ofInternational journal of molecular sciences · 2020Article
- A genome-wide map of circular RNAs in adult zebrafish.Scientific reports · 2019Article
- An Interrogation of Shared and Unique Copy Number Variants Across Genetically Distinct Zebrafish Strains.Zebrafish · 2019Article
- Pattern of fin rays along the antero-posterior axis based on their connection to distal radials.Zoological letters · 2019Article
- Elucidating Gene-by-Environment Interactions Associated with Differential Susceptibility to Chemical Exposure.Environmental health perspectives · 2018Article
- RNA secondary structure profiling in zebrafish reveals unique regulatory features.BMC genomics · 2018Article
- Population genetic diversity in zebrafish lines.Mammalian genome : official journal of the International Mammalian Genome Society · 2018Article
- Loss of the chromatin modifier Kdm2aa causes BrafV600E-independent spontaneous melanoma in zebrafish.PLoS genetics · 2017Article
- Pseudo-De Novo Assembly and Analysis of Unmapped Genome Sequence Reads in Wild Zebrafish Reveal Novel Gene Content.Zebrafish · 2016Article
- The identification of additional zebrafish DICP genes reveals haplotype variation and linkage to MHC class I genes.Immunogenetics · 2016Article
- Working with zebrafish at postembryonic stages.Methods in cell biology · 2016Article
- Article
- SNPfisher: tools for probing genetic variation in laboratory-reared zebrafish.Development (Cambridge, England) · 2015Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
17 authors.
Funding
Abstract
Zebrafish (Danio rerio) is a popular vertebrate model organism largely deployed using outbred laboratory animals. The nonisogenic nature of the zebrafish as a model system offers the opportunity to understand natural variations and their effect in modulating phenotype. In an effort to better characterize the range of natural variation in this model system and to complement the zebrafish reference genome project, the whole genome sequence of a wild zebrafish at 39-fold genome coverage was determined. Comparative analysis with the zebrafish reference genome revealed approximately 5.2 million single nucleotide variations and over 1.6 million insertion-deletion variations. This dataset thus represents a new catalog of genetic variations in the zebrafish genome. Further analysis revealed selective enrichment for variations in genes involved in immune function and response to the environment, suggesting genome-level adaptations to environmental niches. We also show that human disease gene orthologs in the sequenced wild zebrafish genome show a lower ratio of nonsynonymous to synonymous single nucleotide variations.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.